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Extracellular vesicles from dental pulp mesenchymal stem cells modulate macrophage phenotype during acute and chronic cardiac inflammation in athymic nude rats with myocardial infarction

Amaro-Prellezo, Elena; Gómez-Ferrer, Marta; Hakobyan, Lusine; Ontoria-Oviedo, Imelda; Peiró-Molina, Esteban; Tarazona, Sonia; Salguero, Pedro; Ruiz-Saurí, Amparo; Selva-Roldán, Marta; Vives-Sanchez, Rosa; Sepúlveda, Pilar (2024-05-28)

[EN] Background/aims Extracellular vesicles (EVs) derived from dental pulp mesenchymal stem cells (DP-MSCs) are a promising therapeutic option for the treatment of myocardial ischemia. The aim of this study is to determine ...
Modeling Cardiotoxicity in Pediatric Oncology Patients Using Patient-Specific iPSC-Derived Cardiomyocytes Reveals Downregulation of Cardioprotective microRNAs

Reinal-Ferre, Ignacio; Ontoria-Oviedo, Imelda; Selva, Marta; Casini, Marilù; Peiró-Molina, Esteban; Fambuena-Santos, Carlos; Climent, Andreu M.; Balaguer, Julia; Cañete, Adela; Mora, Jaume; Raya, Ángel; Sepúlveda, Pilar (MDPI, 2023-07)

[EN] Anthracyclines are widely used in the treatment of many solid cancers, but their efficacy is limited by cardiotoxicity. As the number of pediatric cancer survivors continues to rise, there has been a concomitant ...

Mostrando ítems 1-2 de 2