Nieuwenhuyse, Enid Van; Martínez-Mateu, Laura; Saiz Rodríguez, Francisco Javier; Panfilov, Alexander V.; Vandersickel, Nele(Elsevier, 2021-06)
[EN] Atrial fibrillation (AF) is the most frequently encountered arrhythmia in clinical practise. One of the major problems in the management of AF is the difficulty in identifying the arrhythmia sources from clinical ...
Sánchez-Arciniegas, Jorge Patricio; Gomez, Juan F; Martínez-Mateu, Laura; Romero Pérez, Lucia; Saiz Rodríguez, Francisco Javier; Trenor Gomis, Beatriz Ana(Frontiers Media SA, 2019-07-04)
[EN] Background: Atrial fibrillation (AF), the most common cardiac arrhythmia, is characterized by alteration of the action potential (AP) propagation. Under persistent AF, myocytes undergo electrophysiological and structural ...
Chowdhury, Md. Kamrul Hasan; Martínez-Mateu, Laura; Do, Jenny; Aromolaran, Kelly A.; Saiz Rodríguez, Francisco Javier; Aromolaran, Ademuyiwa(MDPI AG, 2021-10)
[EN] In the heart, the delayed rectifier K current, I-K, composed of the rapid (I-Kr) and slow (I-Ks) components contributes prominently to normal cardiac repolarization. In lipotoxicity, chronic elevation of pro-inflammatory ...
Riccio, Jennifer; Rocher-Ventura, Sara; Martínez-Mateu, Laura; Alcaine, Alejandro; Saiz Rodríguez, Francisco Javier; Martínez, Juan Pablo; Laguna, Pablo(IEEE, 2020-09-16)
[EN] Atrial fibrosis plays an important role in the pathogenesis of atrial fibrillation (AF). Low bipolar electrograms (b-EGMs) peak-to-peak voltage areas indicate scar tissue and are considered targets for AF substrate ...