Latorre, Marcos; Bersi, Matthew R.; Humphrey, Jay D.(Elsevier, 2019-08)
[EN] Uncontrolled hypertension is a major risk factor for myriad cardiovascular diseases. Among its many effects, hypertension increases central artery stiffness which in turn is both an initiator and indicator of disease. ...
Spronck, Bart; Latorre, Marcos; Wang, Mo; Mehta, Sameet; Caulk, Alexander W.; Ren, Pengwei; Ramachandra, Abhay B.; Murtada, Sae-Il; Rojas, Alexia; He, Chang-Shun; Jiang, Bo; Bersi, Matthew R.; Tellides, George; Humphrey, Jay D.(The Royal Society, 2021-07-28)
[EN] Hypertension induces significant aortic remodelling, often adaptive but sometimes not. To identify immuno-mechanical mechanisms responsible for differential remodelling, we studied thoracic aortas from 129S6/SvEvTac ...