Mayol, Beatriz; Diez-Sánchez, Paula; Sánchez, Alfredo; De La Torre, Cristina; Villalonga, Anabel; Lucena-Sánchez, Elena; Sancenón Galarza, Félix; Martinez-Ruiz, Paloma; Vilela, Diana; Martínez-Máñez, Ramón; Villalonga, Reynaldo(The Royal Society of Chemistry, 2021-11-18)
[EN] This work describes the assembly of a novel enzyme-controlled nanomachine operated through an AND Boolean logic gate for on-command delivery. The nanodevice was constructed on Au-mesoporous silica Janus nanoparticles ...
Pérez-Calabuig, Ana M.; Diez-Sánchez, Paula; Martínez-Ruiz, Paloma; Martínez-Máñez, Ramón; Sánchez, Alfredo; Villalonga, Reynaldo(The Royal Society of Chemistry, 2020-06-14)
[EN] A novel nanomachine for dual and sequential delivery of two different compounds was developed by grafting a thiol group and a pH sensitive beta-cyclodextrin-based gate-like ensemble on acetylcholinesterase-modified ...
Llopis-Lorente, Antoni; de Luis-Fernández, Beatriz; García-Fernández, Alba; Diez, Paula; Sánchez, Alfredo; Marcos Martínez, María Dolores; Villalonga, Reynaldo; Martínez-Máñez, Ramón; Sancenón Galarza, Félix(The Royal Society of Chemistry, 2017)
[EN] We report a delivery system based on Au-mesoporous silica (MS) nanoparticles functionalized with acetylcholinesterase on the Au face as a control unit and with disulfide-containing oligo(ethylene glycol) chains on the ...