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Eukaryotic Initiation Factor 5A2 localizes to actively translating ribosomes to promote cancer cell protrusions and invasive capacity

Martínez-Férriz, Arantxa; Gandía, Carolina; Pardo-Sánchez, José Miguel; Fathinajafabadi, Alihamze; Ferrando Monleón, Alejandro Ramón; Farras, Rosa (BioMed Central, 2023-03-13)

[EN] Background Eukaryotic Initiation Factor 5A (eIF-5A), an essential translation factor, is post-translationally activated by the polyamine spermidine. Two human genes encode eIF-5A, being eIF5-A1 constitutively expressed ...
New roles for AP-1/JUNB in cell cycle control and tumorigenic cell invasion via regulation of cyclin E1 and TGF-B2

Pérez-Benavente, Beatriz; Fathinajafabadi, Alihamze; de la Fuente, Lorena; Gandía, Carolina; Martínez-Férriz, Arantxa; Pardo-Sánchez, José Miguel; Milian-Medina, Lara; Conesa, Ana; Romero, Octavio A.; Carretero, Julián; Matthiesen, Rune; Jariel-Encontre, Isabelle; Piechaczyk, Marc; Farràs, Rosa (BioMed Central Ltd., 2022-12-09)

[EN] Background: JUNB transcription factor contributes to the formation of the ubiquitous transcriptional complex AP-1 involved in the control of many physiological and disease-associated functions. The roles of JUNB in ...

Mostrando ítems 1-2 de 2