Alvarez-Ponce, David; Sabater-Munoz, Beatriz; Toft, Chirstina; Ruíz-González, Mario Javier; Fares Riaño, Mario Ali(Oxford University Press (OUP), 2016-09)
[EN] The Neutral Theory of Molecular Evolution is considered the most powerful theory to understand the evolutionary behavior of proteins. One of the main predictions of this theory is that essential proteins should evolve ...
Aguilar-Rodríguez, Jose; Sabater-Munoz, Beatriz; Montagud-Martinez, Roser; Berlanga, Victor; Alvarez-Ponce, David; Wagner, Andreas; Fares Riaño, Mario Ali(Oxford University Press (OUP), 2016-09)
[EN] Molecular chaperones, also known as heat-shock proteins, refold misfolded proteins and help other proteins reach their native
conformation. Thanks to these abilities, some chaperones, such as the Hsp90 protein or the ...
Fares Riaño, Mario Ali; Keane, O.; Toft, C.; Carretero Paulet, Lorenzo; Jones, G.W.(Public Library of Science, 2013-01)
[EN] Researchers have long been enthralled with the idea that gene duplication can generate novel functions, crediting this process with great evolutionary importance. Empirical data shows that whole-genome duplications ...