[EN] Giardiasis is a parasitism produced by the protozoa Giardia intestinalis that lives as trophozoite in the small intestine (mainly in the duodenum) attached to the intestinal villus by means of billed discs. The first ...
Dea-Ayuela, M. Auxiliadora; Bilbao-Ramos, Pablo; Bolás-Fernández, Francisco; González-Cardenete, Miguel A(Elsevier, 2016-10-04)
Abietane-type diterpenoids, either naturally occurring or synthetic, have shown a wide range of pharmacological actions, including antiprotozoal properties. In this study, we report on the antileishmanial evaluation of a ...
Hamulic, Damir; Stadler, Marco; Hering, Steffen; Padron, Jose M.; Bassett, Rachel; Rivas, Fatima; Loza-Mejia, Marco; Dea-Ayuela, M. Auxiliadora; González-Cardenete, Miguel A(American Chemical Society, 2019-04)
[EN] The first semisynthesis and biological profiling of the new abietane diterpenoid (+)-liquiditerpenoic acid A (abietopinoic acid) (7) along with several analogues are reported. The compounds were obtained from readily ...