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Carbon nanohorns functionalized with polyamidoamine dendrimers as efficient biocarrier materials for gene therapy

Guerra, Javier; Herrero, M. Antonia; Carrión, Blanca; Pérez-Martínez, Francisco C.; Lucío, María Isabel; Rubio, Noelia; Meneghetti, Moreno; Prato, Maurizio; Ceña, Valentín; Vázquez, Ester (Elsevier, 2012-07)

[EN] Carbon nanohorns are suitable platforms for use in biological applications. Their high surface areas allow the incorporation of molecular entities, such as polyamidoamine dendrimers. In this work, we report the ...
Enhanced docetaxel-mediated cytotoxicity in human prostate cancer cells through knockdown of cofilin-1 by carbon nanohorns delivered siRNA.

Pérez-Martínez, Francisco C.; Carrión, Blanca; Lucío, María Isabel; Rubio, Noelia; Herrero, Maria A.; Vázquez, Ester; Ceña, Valentín (Elsevier, 2012-11)

[EN] We synthesized a non-viral delivery system (f-CNH3) for small interfering RNA (siRNA) by anchoring a fourth-generation polyamidoamine dendrimer (G4-PAMAM) to carbon nanohorns (CNHs). Using this new compound, we delivered ...

Mostrando ítems 1-2 de 2