Sousa, Francielle T. G.; Nunes, Cristina; Malta Romano, Camila; Cerdeira Sabino, Ester; González-Cardenete, Miguel A(Universidade de São Paulo (USP), 2020)
[EN] Abietane diterpenoids are naturally occurring plant metabolites with a broad spectrum of biological effects including antibacterial. antileishmanial, antitumor, antioxidant, as well as antiinfiammatory activities. ...
Varbanov, Mihayl; Philippot, Stephanie; González-Cardenete, Miguel A.(MDPI AG, 2023-06)
[EN] The abietane diterpene (+)-ferruginol (1), like other natural and semisynthetic abietanes, is distinguished for its interesting pharmacological properties such as antimicrobial activity, including
antiviral. In this ...
González-Cardenete, Miguel A; Hamulic, Damir; Miquel-Leal, Francisco J.; González-Zapata, Natalia; Jimenez-Jarava, Orlando J.; Brand, Yaneth M.; Restrepo-Mendez, Laura C.; Martinez-Gutierrez, Marlen; Betancur-Galvis, Liliana A.; Marín García, Mª Luisa(American Chemical Society, 2022-08-26)
[EN] Viral infections affect several million patients annually. Although hundreds of viruses are known to be pathogenic, only a few can be treated in the clinic with available antiviral drugs. Naturally based pharmacotherapy ...
González-Cardenete, Miguel A; Rivas, Fatima; Basset, Rachel; Stadler, Marco; Hering, Steffen; Padrón, José M.; Zaragozá, Ramón J.; Dea-Ayuela, Maria Auxiliadora(MDPI AG, 2021-02)
[EN] The abietane-type diterpenoids are significant bioactive compounds exhibiting a varied range of pharmacological properties. In this study, the first synthesis and biological investigation of the new abietane-diterpenoid ...
[EN] The abietane diterpenoids ferruginol (1), tanshinone IIA (3), and carnosol (4) are well-known for their interesting pharmacological properties, including antitumor, similar to other natural and semisynthetic abietanes. ...
Dea-Ayuela, M. Auxiliadora; Bilbao-Ramos, Pablo; Bolás-Fernández, Francisco; González-Cardenete, Miguel A(Elsevier, 2016-10-04)
Abietane-type diterpenoids, either naturally occurring or synthetic, have shown a wide range of pharmacological actions, including antiprotozoal properties. In this study, we report on the antileishmanial evaluation of a ...