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A multiscale computational model of arterial growth and remodeling including Notch signaling

van Asten, Jordy G. M.; Latorre, Marcos; Karakaya, Cansu; Baaijens, Frank P. T.; Sahlgren, Cecilia M.; Ristori, Tommaso; Humphrey, Jay; Loerakker, Sandra (Springer-Verlag, 2023-10)

[EN] Blood vessels grow and remodel in response to mechanical stimuli. Many computational models capture this process phenomenologically, by assuming stress homeostasis, but this approach cannot unravel the underlying ...
Complementary roles of mechanotransduction and inflammation in vascular homeostasis

Latorre, Marcos; Spronck, Bart; Humphrey, Jay D. (The Royal Society, 2021-01-27)

[EN] Arteries are exposed to relentless pulsatile haemodynamic loads, but via mechanical homeostasis they tend to maintain near optimal structure, properties and function over long periods in maturity in health. Numerous ...
Fast, rate-independent, finite element implementation of a 3D constrained mixture model of soft tissue growth and remodeling

Latorre, Marcos; Humphrey, Jay D. (Elsevier, 2020-08-15)

[EN] Constrained mixture models of soft tissue growth and remodeling can simulate many evolving conditions in health as well as in disease and its treatment, but they can be computationally expensive. In this paper, we ...

Mostrando ítems 1-3 de 3