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Multi-objective optimization framework to obtain model-based guidelines for tuning biological synthetic devices: an adaptive network case

Boada Acosta, Yadira Fernanda; Reynoso Meza, Gilberto; Picó Marco, Jesús Andrés; Vignoni, Alejandro (BioMed Central, 2016-03-11)

Background: Model based design plays a fundamental role in synthetic biology. Exploiting modularity, i.e. using biological parts and interconnecting them to build new and more complex biological circuits is one of the key ...
Optimization Alternatives for Robust Model-based Design of Synthetic Biological Circuits

Boada-Acosta, Yadira Fernanda; Pitarch Pérez, Jose Luis; Vignoni, Alejandro; Reynoso Meza, Gilberto; Picó, Jesús (Elsevier, 2016)

[EN] Synthetic biology is reaching the situation where tuning devices by hand is no longer possible due to the complexity of the biological circuits being designed. Thus, mathematical models need to be used in order, not ...
Parameter Identification in Synthetic Biological Circuits Using Multi-Objective Optimization

Boada-Acosta, Yadira Fernanda; Vignoni, Alejandro; Reynoso Meza, Gilberto; Picó, Jesús (Elsevier, 2016)

[EN] Synthetic biology exploits the of mathematical modeling of synthetic circuits both to predict the behavior of the designed synthetic devices, and to help on the selection of their biological coin portents. The increasing ...

Mostrando ítems 1-3 de 3