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Abnormal vascular structure and function within brain metastases is linked to pembrolizumab resistance

Kim, Albert E.; Lou, Kevin W.; Giobbie-Hurder, Anita; Chang, Ken; Gidwani, Mishka; Hoebel, Katharina; Patel, Jay B.; Cleveland, Mason C.; Singh, Praveer; Bridge, Christopher P.; Rakin Ahmed, Syed; Bearce, Benjamin A.; Liu, William; Fuster García, Elíes; Lee, Eudocia Q. (Oxford University Press, 2024-05)

[EN] Background. We recently conducted a phase 2 trial (NCT028865685) evaluating intracranial efficacy of pembrolizumab for brain metastases (BM) of diverse histologies. Our study met its primary efficacy endpoint ...
Algoritmo de detección de metástasis cerebrales en imágenes de resonancia magnética mediante el uso de plantillas tridimensionales de apariencia tumoral

Pérez Ramírez, María Úrsula (Universitat Politècnica de València, 2015-07-31)

[EN] A brain tumor is a pathological intracranial cell growth. It can destroy directly the normal cell population or damage indirectly by invading other parts and cause inflammation, cerebral edema and intracranial pressure. ...
Brain Metastases Detection Methods in Magnetic Resonance Imaging

Pérez-Ramírez, María Úrsula; Arana Fernandez de Moya, Estanislao; Moratal Pérez, David (Institute of Electrical and Electronics Engineers (IEEE), 2016-03)

Early detection of brain metastases increases survival in patients with cancer, since image-guided radiosurgery is the most widely used treatment. As support for the qualitative diagnosis made by radiologists, Computer ...

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Listar por palabra clave "Brain metastases"

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