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Mostrando ítems 1-4 de 4

Diseño modular para terapias antitumorales basadas en bacterias usando biología sintética

Alarcón Ruiz, Iván (Universitat Politècnica de València, 2020-09-15)

[ES] La biología sintética busca aplicar los principios de la ingeniería a los organismos vivos, con el objetivo de controlar y modular su comportamiento. Esta disciplina ha permitido el diseño y construcción de circuitos ...
Glutathione and Bcl-2 targeting facilitates elimination by chemoradiotherapy of human A375 melanoma xenografts overexpressing bcl-xl, bcl-2, and mcl-1

Mena-Mollá, Salvador; Rodríguez, Maria L.; Ortega, Ángel; Priego, Sonia; Obrador, Elena; Asensi, Miguel; Petschen, Ignacio; Cerda, Miguel; Brown, Bob D.; Estrela, Jose M. (BioMed Central, 2012-01-10)

[EN] Background: Bcl-2 is believed to contribute to melanoma chemoresistance. However, expression of Bcl-2 proteins may be different among melanomas. Thus correlations among expression of Bcl-2-related proteins and in vivo ...
Silica-Based Stimuli-Responsive Systems for Antitumor Drug Delivery and Controlled Release

Corma Canós, Avelino; BOTELLA ASUNCION, PABLO; Rivero-Buceta, Eva María (MDPI AG, 2022-01)

[EN] The administration of cytotoxic drugs in classical chemotherapy is frequently limited by water solubility, low plasmatic stability, and a myriad of secondary effects associated with their diffusion to healthy tissue. ...
Tailored cancer therapy by magnetic nanoparticle hyperthermia: A virtual scenario simulation method

Montes-Robles, Roberto; Montanaro, Hazael; Capstick, Myles; Ibáñez Civera, Francisco Javier; Masot Peris, Rafael; Garcia-Breijo, Eduardo; Laguarda-Miro, Nicolas; Martínez-Máñez, Ramón (Elsevier, 2022-10-21)

[EN] Background and objective: Hyperthermia is a cancer treatment aiming to induce cell death by directly warming cancerous tissues above 40 degrees C. This technique can be applied both individually and together with other ...

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