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Listar por palabra clave "Carcinoma, Non-Small-Cell Lung"

Mostrando ítems 1-8 de 8

Analysis of the prognostic value of soluble epidermal growth factor receptor plasma concentration in advanced non-small-cell lung cancer patients

Jantus Lewintre, Eloisa; Sirera Pérez, Rafael; Cabrera, Andrea; Blasco, Ana; Caballero, Cristina; Iranzo, Vega; Rosell, Rafael; Camps, Carlos (Elsevier, 2011-09)

[EN] Background: Epidermal growth factor receptor (EGFR) is overexpressed in a variety of epithelial malignancies including lung cancer. A soluble fragment of the EGFR extracellular domain (sEGFR) can be detected in the ...
Chemotherapy-induced neutropenia does not correlate with DNA repair gene polymorphisms and treatment efficacy in advanced non-small-cell lung cancer patients

Sirera Pérez, Rafael (Elsevier, 2011-07)

[EN] Background: Platinum doublets are standard chemotherapy for advanced non-small-cell lung cancer (NSCLC). The aim of this study was to assess whether neutropenia is: (1) an indicator for treatment efficacy, or (2) ...
Circulating DNA is a useful prognostic factor in patients with advanced non-small cell lung cancer

Sirera Pérez, Rafael; Bremnes, Roy M.; Cabrera, Andrea; Jantus Lewintre, Eloisa; Sanmartin, Elena; Blasco, Ana; del Pozo, Nieves; Rosell, Rafael; Guijarro, Ricardo; Galbis, Jose; Sanchez, Jose Javier; Camps, Carlos (Lippincott, Williams & Wilkins, 2011-02)

Background: Circulating DNA is observed at higher concentrations in patients with lung cancer than in controls. Qualitative and quantitative analysis of circulating DNA is a promising noninvasive tool. Our aim was to ...
Combined VEGF-A and VEGFR-2 concentrations in plasma: diagnostic and prognostic implications in patients with advanced NSCLC

Jantus Lewintre, Eloisa; Sanmartin, Elena; Sirera Pérez, Rafael; Blasco, Ana; Sanchez, Jose Javier; Taron, Miguel; Rosell, Rafael; Camps, Carlos (Elsevier, 2011-11)

Introduction: The vascular endothelial growth factor (VEGF) family of ligands and receptors (VEGFR) play an important role in tumor angiogenesis. Increased expression of angiogenic factors in tumors or in blood is associated ...
Fifth Educational Symposium of the Spanish Lung Cancer Group: report on the Molecular Biology Workshop

Bover, Isabel; Rolfo, Christian; Jantus Lewintre, Eloisa; Sirera Pérez, Rafael; Camps, Carlos; Chaib, Imane; Ramirez-Serrano, Jose L.; Benlloch, Susana; Molina-Vila, Miguel Angel; Simonetti, Sara; Costa, Carlota; Gimenez-Capitan, Ana; Mendez, Pedro; Taron, Miguel; Rosell, Rafael (Elsevier, 2011-12)

The majority of non-small-cell lung cancer (NSCLC) patients present with locally advanced (35%) or metastatic disease (40%); in this setting, it is of the utmost importance to balance efficacy with toxicity. However, with ...
Phase II clinical trial with gemcitabine and paclitaxel sequential monotherapy as first-line treatment for advanced non-small-cell lung cancer (SLCG 01-04)

Iranzo, Vega; Sirera Pérez, Rafael; Carrato, Alfredo; Cabrera, Andrea; Jantus, Eloísa; Guijarro, Ricardo; Sanmartín, Elena; Blasco, Ana; Gil, Mireia; Gómez Aldaraví, Lorenzo; González Larriba, José Luis; Massuti, Bertomeu; Velasco, Amalia; Provencio, Mariano; Rosell, Rafael; Camps, Carlos (Springer, 2011-06)

[EN] Background: In advanced-stage (IIIB or IV) non-small-cell lung cancer (NSCLC), combination chemotherapy has demonstrated response rates of 20% and a 1-year survival rate of 30%. We conducted a multicentre, open-label, ...
The identification of KRAS mutations at codon 12 in plasma DNA is not a prognostic factor in advanced non-small cell lung cancer patients

Camps, Carlos; Jantus Lewintre, Eloisa; Cabrera, Andrea; Blasco, Ana; Sanmartin, Elena; Gallach, Sandra; Caballero, Cristina; del Pozo, Nieves; Rosell, Rafael; Guijarro, Ricardo; Sirera Pérez, Rafael (Elsevier, 2011-06)

Qualitative analysis of circulating DNA in the blood is a promising non-invasive diagnostic and prognostic tool. Our aim was to study the association between the presence of KRAS mutations at codon 12 and several clinical ...
The role of tumor-infiltrating immune cells and chronic inflammation at the tumor site on cancer development, progression, and prognosis: emphasis on non-small cell lung cancer

Bremnes, Roy M.; Al-Shibli, Khalid; Donnem, Tom; Sirera Pérez, Rafael; Al-Saad, Samer; Andersen, Sigve; Stenvold, Helge; Camps, Carlos; Busund, Lill-Tove (Lippincott, Williams & Wilkins, 2011-04)

[EN] In addition to malignant neoplastic cells, cancer tissues also include immune cells, fibroblasts, and endothelial cells, including an abundant collection of growth factors, proangiogenic mediators, cytokines, chemokines, ...

Mostrando ítems 1-8 de 8

Listar por palabra clave "Carcinoma, Non-Small-Cell Lung"

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Listar por palabra clave "Carcinoma, Non-Small-Cell Lung"