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Listar por palabra clave "Cell differentiation"

Mostrando ítems 1-17 de 17

A change of developmental program induces the remodeling of the interchromatin domain during microspore embryogenesis in Brassica napus L

Seguí-Simarro, Jose M.; Corral Martínez, Patricia; Corredor, E.; Raska, I.; Testillano, P. S.; Risueno, M.C. (Elsevier, 2011-05-15)

After a stress treatment, in vitro-cultured pollen changes its normal gametophytic developmental pathway towards embryogenesis producing multicellular embryos from which, finally, haploid and double haploid plants develop. ...
Análisis funcional del regulador de la diferenciación celular MpRIMA en Marchantia polymorpha

Brito Gutiérrez, Pavel (Universitat Politècnica de València, 2023-02-08)

[ES] Las plantas tienen la capacidad de adaptar sus programas de desarrollo para hacer frente a los cambios que se producen en su entorno, que en ocasiones son adversos, con el fin de asegurar su supervivencia. Para modificar ...
BIOLOGICAL ACTIVITY OF FIBRONECTIN AT THE CELL-MATERIAL INTERFACE

González García, Cristina (Universitat Politècnica de València, 2012-11-05)

Esta tesis aborda la actividad biológica de la fibronectina (FN) como proteína de interfase en la interacción célula-material. La tesis investiga la respuesta de la proteína, en términos de cantidad adsorbida y conformación, ...
Controlled Assembly of Fibronectin Nanofibrils Triggered by Random Copolymer Chemistry

MNATSAKANYAN, HAYK; Rico Tortosa, Patricia María; Grigoriou, Eleni; Maturana Candelas, Aarón; Rodrigo Navarro, Aleixandre; Salmerón Sánchez, Manuel; Sabater i Serra, Roser (American Chemical Society, 2015-08-19)

Fibronectin fibrillogenesis is the physiological process by which cells elaborate a fibrous FN matrix. Poly(ethyl acrylate), PEA, has been described to induce a similar process upon simple adsorption of fibronectin (FN) ...
Desarrollo de una plataforma de diferenciación 3D bioimpresa empleando agregados celulares de células madre mesenquimales humanas del tejido adiposo

López Cuquerella, Alejandro (Universitat Politècnica de València, 2021-10-14)

[ES] Este proyecto tiene como objetivo la creación de una plataforma de diferenciación 3D mediante la bioimpresión de agregados celulares de células madre humanas derivadas de tejido adiposo (hASCs) con distintas densidades ...
Effect of topological cues on material-driven fibronectinfibrillogenesis and cell differentiation

Ballester Beltrán, José; Cantini, Marco; Lebourg, Myriam Madeleine; Rico Tortosa, Patricia María; Moratal Pérez, David; García, Andrés J.; Salmerón Sánchez, Manuel (Springer Verlag (Germany), 2012-01)

[EN] Fibronectin (FN) assembles into fibrillar networks by cells through an integrin-dependent mechanism. We have recently shown that simple FN adsorption onto poly(ethyl acrylate) surfaces (PEA), but not control polymer ...
Estudio del comportamiento de hepatocitos en hidrogeles de origen natural para terapia celular hepática

Rodríguez Fernández, Julio (Universitat Politècnica de València, 2019-07-03)

[ES] La terapia celular hepática (TCH) se concibe como una potencial opción terapéutica para recuperar y estabilizar la función metabólica perdida en enfermedades hepáticas de distinta etiología para mejorar los resultados ...
Estudio del patrón de expresión génica de Miniyo en Marchantia Polymorpha

Escalante Ramírez, Cristina (Universitat Politècnica de València, 2020-09-25)

[ES] La diferenciación celular es un proceso fundamental y necesario para el desarrollo de las diferentes estructuras y órganos que componen los organismos multicelulares. Sin embargo, a pesar de su importancia, se sabe ...
Fibronectin distribution on demixed nanoscale topographies

Perez Garnes, Manuel; González García, Cristina; Moratal Pérez, David; Rico Tortosa, Patricia María; Salmerón Sánchez, Manuel (Wichtig Editore, 2011-02-04)

[EN] Purpose: It is known that surface nanotopography influences cell adhesion and differentiation. Our aim is to analyze the effect of nanoscale topography on fibronectin adsorption and, afterwards, on cell adhesion in ...
Fine-Tuning Regulation of Surface Mobility by Acrylate Copolymers and Its Effect on Cell Adhesion and Differentiation

Morata-Martínez, Miranda; Sprott, Mark R.; Antolinos-Turpín, Carmen M.; Salmerón Sánchez, Manuel; Gallego-Ferrer, Gloria (2023-04-17)

[EN] Fibronectin (FN) mediates cell-material interactions during events such as tissue repair, and therefore the biomimetic modeling of this protein in vitro benefits regeneration. The nature of the interface is crucial ...
Functionalization of PLLA with Polymer Brushes to Trigger the Assembly of Fibronectin into Nanonetworks

Sprott, Mark Robert; Gallego-Ferrer, Gloria; Dalby, Matthew J.; Salmerón Sánchez, Manuel; Cantini, Marco (Wiley-VCH, 2019-02-07)

[EN] Poly-l-lactic acid (PLLA) has been used as a biodegradable polymer for many years; the key characteristics of this polymer make it a versatile and useful resource for regenerative medicine. However, it is not inherently ...
Material-driven fibronectin fibrillogenesis to engineer cell function

Llopis Hernández, Virginia (Universitat Politècnica de València, 2017-11-03)

This thesis ventures with the extracellular matrix protein (ECM) fibronectin (FN) as an interface protein in the interaction between cells and materials to design microenvironment for future use in tissue engineering. It ...
Papel del interruptor binario de la diferenciación celular MINIYO/RIMA en el desarrollo del óvulo en Arabidopsis thaliana

Voldman Echave, Maite (Universitat Politècnica de València, 2021-09-02)

[ES] Debido a la importancia de las semillas como base de la alimentación, conocer los mecanismos moleculares que determinan su producción y el tamaño de las mismas es de especial interés para conseguir una mejora en el ...
Parthenogenic blastocysts cultured under in vivo conditions exhibit proliferation and differentiation expression genes similar to those of normal embryos

Naturil Alfonso, Carmen; Saenz de Juano Ribes, María de los Desamparados; Peñaranda, D.S.; Vicente Antón, José Salvador; Marco Jiménez, Francisco (Elsevier Masson, 2011)

Parthenote embryos offer multiple possibilities in biotechnological investigation, such as stem cell research. However, there is still a dearth of knowledge of this kind of embryo. In this study, development and ploidy ...
PCL-coated hydroxyapatite scaffold derived from cuttlefish bone: in vitro cell culture studies

Milovac, Dajana; Gamboa-Martinez, Tatiana C.; Ivankovic, Marica; Gallego-Ferrer, Gloria; Ivankovic, Hrvoje (Elsevier, 2014-09-01)

[EN] In the present study, we examined the potential of using highly porous poly(epsilon-caprolactone) (PCL)-coated hydroxyapatite (HAp) scaffold derived from cuttlefish bone for bone tissue engineering applications. The ...
Role of material-driven fibronectin fibrillogenesis in cell differentiation

Salmerón Sánchez, Manuel; Rico Tortosa, Patricia María; Moratal Pérez, David; Lee, Ted T.; Schwarzbauer, Jean E.; Garcia, Andres J. (Elsevier, 2011)

Fibronectin (FN) is a ubiquitous extracellular matrix protein (ECM) protein that is organized into fibrillar networks by cells through an integrin-mediated process that involves contractile forces. This assembly allows for ...
Sandwich-like systems to engineer the cellular microenvironment

Ballester Beltrán, José (Universitat Politècnica de València, 2015-03-20)

Abstract While most of the in vitro cultures are carried out on bi-dimensional (2D) substrates, most of the in vivo extracellular matrices are threedimensional (3D). Consequently cells behave differently on 2 ...