Molina Serrano, Diego; Marques Signes, Jorge; Nohales Zafra, Maria Angeles; Flores Pedauye, Ricardo; Daros Arnau, Jose Antonio(Taylor & Francis: STM, Behavioural Science and Public Health Titles, 2012-03)
[EN] Bacteria and archaea contain a 2'-5' RNA ligase that seals in vitro 2',3'-cyclic phosphodiester and 5'-hydroxyl RNA termini, generating a 2',5'-phosphodiester bond. In our search for an RNA ligase able to circularize ...
Cordero-Cucart, María Teresa; Aragonés, V.; Daros Arnau, Jose Antonio(Journal of Visualized Experiments, 2018)
[EN] With increasing interest in RNA biology and the use of RNA molecules in sophisticated biotechnological applications, the methods to produce large amounts of recombinant RNAs are limited. Here, we describe a protocol ...
Cordero-Cucart, María Teresa; Ortolá-Navarro, Beltrán; Daros Arnau, Jose Antonio(Frontiers Media SA, 2018)
[EN] Eggplant latent viroid (ELVd) is a relatively small non-coding circular RNA that induces asymptomatic infections in eggplants (Solanum melongena L.). Like other viroid species that belong to the family Avsunviroidae, ...
Cervera, Amelia; Urbina, Denisse; La Peña del Rivero, Marcos de(BioMed Central, 2016-06-23)
[EN] Background: Catalytic RNAs, or ribozymes, are regarded as fossils of a prebiotic RNA world that have remained in
the genomes of modern organisms. The simplest ribozymes are the small self-cleaving RNAs, like the ...
Muñoz Triviño, Jorge Jaime(Universitat Politècnica de València, 2021-07-30)
[ES] En el contexto de una pandemia mundial, ocasionada por el virus SARS-CoV2, que ha provocado más de cuatro millones de fallecidos en apenas más de un año, el surgimiento de nuevas estrategias terapéuticas para luchar ...
[EN] Viroids are a unique type of infectious agent, exclusively composed of a relatively small
(246¿430 nt), highly base-paired, circular, non-coding RNA. Despite the small size and non-coding
nature, the more-than-thirty ...