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Gated Mesoporous Silica Nanocarriers for a "two-Step" Targeted System to Colonic Tissue

Gonzalez-Alvarez, Marta; Coll Merino, Mª Carmen; Gonzalez-Alvarez, Isabel; Giménez Morales, Cristina; Aznar, Elena; Martínez-Bisbal, M.Carmen; Lozoya Agulló, Isabel; Bermejo, M.; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (American Chemical Society, 2017)

[EN] Colon targeted drug delivery is highly relevant not only to treat colonic local diseases but also for systemic therapies. Mesoporous silica nanoparticles (MSNs) have been demonstrated as useful systems for controlled ...
Mesoporous silica microparticles gated with a bulky azo derivative for the controlled release of dyes/ drugs in colon

Ferri, Daniel; Gaviña, Pablo; Parra Álvarez, Margarita; Costero, Ana M.; El Haskouri, Jamal; Amorós del Toro, Pedro; Merino Sanjuán, Virginia; Teruel, Adrián H; Sancenón Galarza, Félix; Martínez-Máñez, Ramón (The Royal Society, 2018-08)

[EN] Mesoporous silica microparticles were prepared, loaded with the dye safranin O (M-Saf) or with the drug budesonide (M-Bud) and capped by the grafting of a bulky azo derivative. Cargo release from M-Saf at different ...
Smart drug delivery systems designed to improve Inflammatory Bowel Disease therapy

Hernández Teruel, Adrián (Universitat Politècnica de València, 2019-10-21)

[ES] La presente tesis doctoral titulada "Sistemas de liberacio'n controlada de fa'rmacos diseñados para mejorar el tratamiento de Enfermedad Inflamatoria Intestinal" se centra en el diseño, preparación, caracterización y ...
Smart gated magnetic silica mesoporous particles for targeted colon drug delivery: New approaches for inflammatory bowel diseases treatment

Teruel, Adrian H.; Pérez-Esteve, Édgar; Gonzalez-Alvarez, Isabel; Gonzalez -Alvarez, Marta; Costero, Ana M.; Ferri, Daniel; Parra Álvarez, Margarita; Gaviña, Pablo; Merino Sanjuán, Virginia; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (Elsevier, 2018)

[EN] Magnetic mesoporous silica microparticles were loaded with safranin O (S1) and with hydrocortisone (S2) and the outer surface functionalized with a bulky azo derivative bearing urea moieties. Aqueous suspensions of ...

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Listar por palabra clave "Colon targeting"

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