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Listar por palabra clave "Comprehensive In Vitro Proarrhythmia Assay (CiPA)"

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Experimentally Validated Modeling of Dynamic Drug-hERG Channel Interactions Reproducing the Binding Mechanisms and its Importance in Action Potential Duration

Escobar Ropero, Fernando; Friis, Soren; Adly, Nouran; Brinkwirth, Nina; Gomis-Tena Dolz, Julio; Saiz Rodríguez, Francisco Javier; Arne Klaerke, Dan; Stoelzle-Feix, Sonja; Romero Pérez, Lucia (Universitat Politècnica de València, 2024-06-08)

Background and Objective: Assessment of drug cardiotoxicity is critical in the development of new compounds and modeling of drug-binding dynamics to hERG can improve early cardiotoxicity assessment. We previously developed ...

Mostrando ítems 1-1 de 1