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Listar por palabra clave "Constraint-based model"

Mostrando ítems 1-5 de 5

Dynamic estimations of metabolic fluxes with constraint-based models and possibility theory

Llaneras Estrada, Francisco; Sala, Antonio; Picó Marco, Jesús Andrés (Elsevier, 2012-12)

Living cells can be modelled by successively imposing known constraints that limit their behaviour, such as mass balances, thermodynamic laws or enzyme capacities. The resulting constraint-based models enclose all the ...
Estimation of recombinant protein production in Pichia pastoris base don a constraint-based model

Tortajada Serra, Marta; Llaneras Estrada, Francisco; Ramón, D.; Picó, Jesús (ELSEVIER SCI LTD, 2012-07)

[EN] A previously validated constraint based model and possibilistic MFA have been used to design a simple estimator of protein production rate in Pichia pastoris cultures. A structured model of the yeast P. pastoris ...
Interval and Possibilistic Methods for Constraint-Based Metabolic Models

Llaneras Estrada, Francisco (Universitat Politècnica de València, 2011-03-23)

This thesis is devoted to the study and application of constraint-based metabolic models. The objective was to find simple ways to handle the difficulties that arise in practice due to uncertainty (knowledge is incomplete, ...
Process development for the obtention and use of recombinant glycosidases: expression, modelling and immobilisation

Tortajada Serra, Marta (Universitat Politècnica de València, 2012-07-23)

El objetivo general de la presente tesis doctoral es el desarrollo de herramientas para la obtencion, produccion y aplicacion de dos enzimas glicosidicas: �¿-L-arabinofuranosidasa proveniente del hongo Aspergillus niger ...
Validation of a FBA model for Pichia pastoris in chemostat cultures

Morales, Yeimy; Tortajada, Marta; Picó Marco, Jesús Andrés; Vehi, Josep; Llaneras, Francisco (BioMed Central, 2014-12-24)

Background: Constraint-based metabolic models and flux balance analysis (FBA) have been extensively used in the last years to investigate the behavior of cells and also as basis for different industrial applications. In ...