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Listar por palabra clave "Docetaxel"

Mostrando ítems 1-7 de 7

Analysis of the prognostic value of soluble epidermal growth factor receptor plasma concentration in advanced non-small-cell lung cancer patients

Jantus Lewintre, Eloisa; Sirera Pérez, Rafael; Cabrera, Andrea; Blasco, Ana; Caballero, Cristina; Iranzo, Vega; Rosell, Rafael; Camps, Carlos (Elsevier, 2011-09)

[EN] Background: Epidermal growth factor receptor (EGFR) is overexpressed in a variety of epithelial malignancies including lung cancer. A soluble fragment of the EGFR extracellular domain (sEGFR) can be detected in the ...
Chemotherapy-induced neutropenia does not correlate with DNA repair gene polymorphisms and treatment efficacy in advanced non-small-cell lung cancer patients

Sirera Pérez, Rafael (Elsevier, 2011-07)

[EN] Background: Platinum doublets are standard chemotherapy for advanced non-small-cell lung cancer (NSCLC). The aim of this study was to assess whether neutropenia is: (1) an indicator for treatment efficacy, or (2) ...
Circulating DNA is a useful prognostic factor in patients with advanced non-small cell lung cancer

Sirera Pérez, Rafael; Bremnes, Roy M.; Cabrera, Andrea; Jantus Lewintre, Eloisa; Sanmartin, Elena; Blasco, Ana; del Pozo, Nieves; Rosell, Rafael; Guijarro, Ricardo; Galbis, Jose; Sanchez, Jose Javier; Camps, Carlos (Lippincott, Williams & Wilkins, 2011-02)

Background: Circulating DNA is observed at higher concentrations in patients with lung cancer than in controls. Qualitative and quantitative analysis of circulating DNA is a promising noninvasive tool. Our aim was to ...
Combined VEGF-A and VEGFR-2 concentrations in plasma: diagnostic and prognostic implications in patients with advanced NSCLC

Jantus Lewintre, Eloisa; Sanmartin, Elena; Sirera Pérez, Rafael; Blasco, Ana; Sanchez, Jose Javier; Taron, Miguel; Rosell, Rafael; Camps, Carlos (Elsevier, 2011-11)

Introduction: The vascular endothelial growth factor (VEGF) family of ligands and receptors (VEGFR) play an important role in tumor angiogenesis. Increased expression of angiogenic factors in tumors or in blood is associated ...
Prostate cancer chemotherapy by intratumoral administration of Docetaxel-Mesoporous silica nanomedicines

Rivero-Buceta, Eva María; Bernal-Gómez, Adrián; VIDAURRE-AGUT, CARLA; Lopez Moncholi, Eric; Benlloch Baviera, Jose María; Moreno Manzano, Victoria; Vera Donoso, César David; BOTELLA ASUNCION, PABLO (Elsevier, 2024-10-25)

[EN] Docetaxel (DTX) is a recommended treatment in patients with metastasic prostate cancer (PCa), despite its therapeutic efficacy is limited by strong systemic toxicity. However, in localized PCa, intratumoral (IT) ...
Silica-Based Stimuli-Responsive Systems for Antitumor Drug Delivery and Controlled Release

Corma Canós, Avelino; BOTELLA ASUNCION, PABLO; Rivero-Buceta, Eva María (MDPI AG, 2022-01)

[EN] The administration of cytotoxic drugs in classical chemotherapy is frequently limited by water solubility, low plasmatic stability, and a myriad of secondary effects associated with their diffusion to healthy tissue. ...
The identification of KRAS mutations at codon 12 in plasma DNA is not a prognostic factor in advanced non-small cell lung cancer patients

Camps, Carlos; Jantus Lewintre, Eloisa; Cabrera, Andrea; Blasco, Ana; Sanmartin, Elena; Gallach, Sandra; Caballero, Cristina; del Pozo, Nieves; Rosell, Rafael; Guijarro, Ricardo; Sirera Pérez, Rafael (Elsevier, 2011-06)

Qualitative analysis of circulating DNA in the blood is a promising non-invasive diagnostic and prognostic tool. Our aim was to study the association between the presence of KRAS mutations at codon 12 and several clinical ...

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