[EN] Background: Assessment of drug cardiac safety is critical in the development of new compounds and is commonly addressed by evaluating the half-maximal blocking concentration of the potassium human ether-à-go-go related ...
Dux-Santoy Hurtado, Lydia; Sebastián Aguilar, Rafael; Felix-Rodriguez, Jose; Ferrero De Loma-Osorio, José María; Saiz Rodríguez, Francisco Javier(IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, 2011)
[EN] The use of antiarrhythmic drugs is common to treat heart rhythm disorders. Computational modeling and simulation are promising tools that could be used to investigate the effects of specific drugs on cardiac ...