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Mostrando ítems 1-5 de 5

Expression, localization and acetylation level of heterogeneous ribonucleoproteins (hnRNPs) depending on KRAS mutational status in colorectal cancer cell lines

González Rodríguez, Patricia (Universitat Politècnica de València, 2015-06-17)

[EN] Mutations in KRAS have been associated with resistance to anti-EGFR drugs and with a worse prognosis in colorectal cancer (CRC). KRAS membrane is a GTPase that transduce the extracellular signal from the cytoplasms ...
Fifth Educational Symposium of the Spanish Lung Cancer Group: report on the Molecular Biology Workshop

Bover, Isabel; Rolfo, Christian; Jantus Lewintre, Eloisa; Sirera Pérez, Rafael; Camps, Carlos; Chaib, Imane; Ramirez-Serrano, Jose L.; Benlloch, Susana; Molina-Vila, Miguel Angel; Simonetti, Sara; Costa, Carlota; Gimenez-Capitan, Ana; Mendez, Pedro; Taron, Miguel; Rosell, Rafael (Elsevier, 2011-12)

The majority of non-small-cell lung cancer (NSCLC) patients present with locally advanced (35%) or metastatic disease (40%); in this setting, it is of the utmost importance to balance efficacy with toxicity. However, with ...
Interacción con ligandos celulares de los dominios SH3 del adaptador CIN85 en la regulación del EGFR

Castellá Giner, Moisés (Universitat Politècnica de València, 2016-09-29)

[ES] Relevancia del EGFR El receptor del Factor de crecimiento epidérmico (EGFR) es un receptor del tipo tirosina quinasa (RTK). La interacción con su ligando natural (el Factor de crecimiento epidérmico, EGF) es la ...
Phase II clinical trial with gemcitabine and paclitaxel sequential monotherapy as first-line treatment for advanced non-small-cell lung cancer (SLCG 01-04)

Iranzo, Vega; Sirera Pérez, Rafael; Carrato, Alfredo; Cabrera, Andrea; Jantus, Eloísa; Guijarro, Ricardo; Sanmartín, Elena; Blasco, Ana; Gil, Mireia; Gómez Aldaraví, Lorenzo; González Larriba, José Luis; Massuti, Bertomeu; Velasco, Amalia; Provencio, Mariano; Rosell, Rafael; Camps, Carlos (Springer, 2011-06)

[EN] Background: In advanced-stage (IIIB or IV) non-small-cell lung cancer (NSCLC), combination chemotherapy has demonstrated response rates of 20% and a 1-year survival rate of 30%. We conducted a multicentre, open-label, ...
Profile of the Roche cobas (R) EGFR mutation test for non-small cell lung cancer

Malapelle, Umberto; Sirera Pérez, Rafael; Jantus-Lewintre, Eloisa; Reclusa, P.; Calabuig-Farinas, S.; Blasco, Ana; Pisapia, P.; Rolfo, C.; Camps, Carlos (Taylor & Francis, 2017)

[EN] Introduction: The discovery of driver mutations in non-small cell lung cancer (NSCLC) has led to the development of genome-based personalized medicine. Fifteen to 20% of adenocarcinomas harbor an epidermal growth ...

Mostrando ítems 1-5 de 5

Listar por palabra clave "EGFR"

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