Rodrigo Tarrega, Guillermo; Fares Riaño, Mario Ali(BioMed Central, 2012-04-13)
Background: The potential role of RNA molecules as gene expression regulators has led to a new perspective on the intracellular control and genome organization. Because secondary structures are crucial for their regulatory ...
Rodrigo Tarrega, Guillermo; Elena Fito, Santiago Fco(Oxford University Press (OUP), 2013)
Robustness is considered a ubiquitous property of living systems at all levels of organization, and small noncoding RNA (sncRNA) is a genuine model for its study at the molecular level. In this communication, we question ...
[EN] Biological systems are resistant to perturbations caused by the environment and by the intrinsic noise of the system. Robustness to mutations is a particular aspect of robustness in which the phenotype is resistant ...
de Visser, J. Arjan G. M.; Cooper, Tim F.; Elena Fito, Santiago Fco(Royal Society, The, 2011-12-22)
[EN] Since Bateson's discovery that genes can suppress the phenotypic effects of other genes, gene interactions-called epistasis-have been the topic of a vast research effort. Systems and developmental biologists study ...