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Listar por palabra clave "Femtosecond transient absorption"

Mostrando ítems 1-3 de 3

Characterization of Locally Excited and Charge-Transfer States of the Anticancer Drug Lapatinib by Ultrafast Spectroscopy and Computational Studies

Vayá Pérez, Ignacio; Andreu Ros, María Inmaculada; Lence, Emilio; González-Bello, Concepción; Cuquerella Alabort, Maria Consuelo; Navarrete-Miguel, Miriam; Roca-Sanjuán, Daniel; Miranda Alonso, Miguel Ángel (John Wiley & Sons, 2020-12-04)

[EN] Lapatinib (LAP) is an anticancer drug, which is metabolized to theN- and O-dealkylated products (N-LAP andO-LAP, respectively). In view of the photosensitizing potential of related drugs, a complete experimental and ...
Mechanistic Studies on the Photochemical Formation and Cleavage of Oxetanes Derived from Pyrimidine Bases

Blasco Brusola, Alejandro (Universitat Politècnica de València, 2021-04-13)

[ES] La luz solar puede producir daños en el ADN por absorción directa de luz UVB, o por fotosensibilización tras la absorción de luz UVA por parte de fármacos, que pueden actuar como fotosensibilizadores (PS). La benzofenona ...
Protein binding of lapatinib and its N- and O-dealkylated metabolites interrogated by fluorescence, ultrafast spectroscopy and molecular dynamics simulations

Andreu Ros, María Inmaculada; Lence, Emilio; González-Bello, Concepción; Mayorga, Cristobalina; Cuquerella Alabort, Maria Consuelo; Vayá Pérez, Ignacio; Miranda Alonso, Miguel Ángel (Frontiers Media SA, 2020-10-30)

[EN] Lapatinib (LAP) is an anticancer drug generally used to treat breast and lung cancer. It exhibits hypersensitivity reactions in addition to dermatological adverse effects and photosensitivity. Moreover, LAP binds to ...

Mostrando ítems 1-3 de 3

Listar por palabra clave "Femtosecond transient absorption"

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Listar por palabra clave "Femtosecond transient absorption"