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Listar por palabra clave "G-quadruplex"

RiuNet: Repositorio Institucional de la Universidad Politécnica de Valencia

Listar por palabra clave "G-quadruplex"

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    Mechanical unfolding of long human telomeric RNA (TERRA) 
    Garavís, M.; Bocanegra, R.; Herrero-Galán, E.; González, C.; Villasante, A.; Arias-Gonzalez, J. R. (The Royal Society of Chemistry, 2013)
    [EN] We report the first single molecule investigation of TERRA molecules. By using optical-tweezers and other biophysical techniques, we have found that long RNA constructions of up to 25 GGGUUA repeats form higher order ...
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    Mesoscopic model for DNA G-quadruplex unfolding 
    Bergues-Pupo, A.E.; Gutiérrez, I.; Arias-Gonzalez, J. R.; Falo, F.; Fiasconaro, A. (Nature Publishing Group, 2017-09-18)
    [EN] Genomes contain rare guanine-rich sequences capable of assembling into four-stranded helical structures, termed G-quadruplexes, with potential roles in gene regulation and chromosome stability. Their mechanical unfolding ...
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    Role of the central cations in the mechanical unfolding of DNA and RNA G-quadruplexes 
    Bergues-Pupo, A.E.; Arias-Gonzalez, J. R.; Moron, M.C.; Fiasconaro, A.; Falo, F. (Oxford University Press, 2015-09-03)
    [EN] Cations are known to mediate diverse interactions in nucleic acids duplexes but they are critical in the arrangement of four-stranded structures. Here, we use all- atom molecular dynamics simulations with explicit ...
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    Single-Stranded Condensation Stochastically Blocks G-Quadruplex Assembly in Human Telomeric RNA 
    Gutiérrez, I.; Garavís, M.; de Lorenzo, S.; Villasante, A.; González, C.; Arias-Gonzalez, J. R. (American Chemical Society, 2018-05-17)
    [EN] TERRA is an RNA molecule transcribed from human subtelomeric regions toward chromosome ends potentially involved in regulation of heterochromatin stability, semiconservative replication, and telomerase inhibition, ...
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    Síntesis y caracterización de poliaminas tripodales para el reconocimiento de ADN no canónico 
    Navarro Hernández, María (Universitat Politècnica de València, 2024-09-02)
    [ES] Las estructuras G-cuádruplex son formaciones secundarias del DNA que adoptan algunos telómeros y regiones promotoras de genes implicados en el cáncer. El trabajo fin de grado se pretende sintetizar y caracterizar una ...