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Listar por palabra clave "Gated materials"

Mostrando ítems 1-20 de 21

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A Mycoplasma Genomic DNA Probe using Gated Nanoporous Anodic Alumina

Pla, Luis; Xifre Perez, Elisabet; Ribes, Àngela; Aznar, Elena; Marcos Martínez, María Dolores; Marsal, L.F.; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (John Wiley & Sons, 2017)

[EN] A nanoporous anodic alumina (NAA)-based sensor system for the detection of Mycoplasma was developed through the implementation of "molecular gates" selective to the presence of this bacterium. The capped support showed ...
Aptamer-Capped Nanoporous Anodic Alumina for SARS-CoV-2 Spike Protein Detection

Caballos-Gómez, María Isabel; Aranda, María Nieves; López-Palacios, Alba; Pla, Luis; Santiago Felipe, Sara; Hernández-Montoto, Andy; Tormo-Mas, María Ángeles; Pemán, Javier; Gómez-Ruiz, María Dolores; Calbuig, Eva; Sánchez-Sendra, Beatriz; Francés-Gómez, Clara; Geller, Ron; Aznar, Elena; Martínez-Máñez, Ramón (Wiley-VCH Verlag GmbH & Co. KGaA, 2023-06)

[EN] The COVID-19 pandemic, which began in 2019, has highlighted the importance of testing and tracking infected individuals as a means of mitigating the spread of the virus. In this context, the development of sensitive ...
Aptamer-Capped nanoporous anodic alumina for Staphylococcus aureus detection

Pla, Luis; Santiago Felipe, Sara; Tormo-Mas, María Ángeles; Pemán, Javier; Sancenón Galarza, Félix; Aznar, Elena; Martínez-Máñez, Ramón (Elsevier, 2020-10-01)

[EN] The development of new detection systems for an accurate and rapid identification of pathogens has become an essential challenge in the biomedical field. Herein a highly selective platform based on aptamer-gated nano ...
Delivery modulation in silica mesoporous supports via functionalization in the pore outlets with a Zn(II) bis(2-pyridylmethyl)amine complex

Bartovsky, Pavel; Ribes, Àngela; Agostini, Alessandro; Benito Beorlegui, Ángel; Martínez-Máñez, Ramón (Elsevier, 2014-06-01)

[EN] This paper focuses on the study of the release behaviour of an entrapped dye (i.e. [Ru(bipy)3] 2+) in the presence of different anions from silica mesoporous supports functionalized in the external surface ...
Double Drug Delivery Using Capped Mesoporous Silica Microparticles for the Effective Treatment of Inflammatory Bowel Disease

Hernández Teruel, Adrián; Pérez-Esteve, Édgar; González-Álvarez, Isabel; González-Álvarez, Marta; Costero Nieto, Ana María; Ferri, Daniel; Gaviña, Pablo; Merino Sanjuán, Virginia; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (American Chemical Society, 2019-06)

[EN] Silica mesoporous microparticles loaded with both rhodamine B fluorophore (S1) or hydrocortisone (S2), and capped with an olsalazine derivative, are prepared and fully characterized. Suspensions of Si and S2 in water ...
Enhanced Efficacy and Broadening of Antibacterial Action of Drugs Via the Use of Capped Mesoporous Nanoparticles

Mas Font, Nuria; Galiana Guillem, Irene; Mondragón Martínez, Laura; Aznar Gimeno, Elena; Climent Terol, Estela; Cabedo Escrig, Nuria; Sancenón Galarza, Félix; Murguía Ibáñez, José Ramón; Martínez Mañez, Ramón; Marcos Martínez, María Dolores; Amoros del Toro, Pedro (Wiley-VCH Verlag, 2013-07-09)

[EN] A novel nanodevice consisting of mesoporous nanoparticles loaded with vancomycin and capped with epsilon-poly-L-lysine (epsilon-PL) was prepared and its interaction with different Gram-negative bacteria studied. A ...
Enzyme-Responsive Silica Mesoporous Supports Capped with Azopyridinium Salts for Controlled Delivery Applications

Mas Font, Nuria; Agostini, Alessandro; Mondragón Martínez, Laura; Bernardos Bau, Andrea; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Martínez Mañez, Ramón; Costero Nieto, Ana María; Gil Grau, Salvador; Merino Sanjuán, María Matilde; Amoros del Toro, Pedro Jose; Orzáez Calatayud, Mar; Pérez Payá, Enrique (Wiley-VCH Verlag, 2012-12-07)

The preparation of a new capped silica mesoporous material, Rh-Azo-S, for on-command delivery applications in the presence of target enzymes is described. The material consists of nanometric mesoporous MCM-41-like supports ...
Exploring the Synergy between Nano-Formulated Linezolid and Polymyxin B as a Gram-Negative Effective Antibiotic Delivery System Based on Mesoporous Silica Nanoparticles

Otri, Ismael; Medaglia, Serena; Martínez-Máñez, Ramón; Aznar, Elena; Sancenón Galarza, Félix (MDPI AG, 2024-01)

[EN] Antimicrobial resistance is a current silent pandemic that needs new types of antimicrobial agents different from the classic antibiotics that are known to lose efficiency over time. Encapsulation of antibiotics inside ...
Gated Mesoporous Silica Nanocarriers for a "two-Step" Targeted System to Colonic Tissue

Gonzalez-Alvarez, Marta; Coll Merino, Mª Carmen; Gonzalez-Alvarez, Isabel; Giménez Morales, Cristina; Aznar, Elena; Martínez-Bisbal, M.Carmen; Lozoya Agulló, Isabel; Bermejo, M.; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (American Chemical Society, 2017)

[EN] Colon targeted drug delivery is highly relevant not only to treat colonic local diseases but also for systemic therapies. Mesoporous silica nanoparticles (MSNs) have been demonstrated as useful systems for controlled ...
Gated Mesoporous Silica Nanoparticles Using a Double-Role Circular Peptide for the Controlled and Target-Preferential Release of Doxorubicin in CXCR4-Expresing Lymphoma Cells

De La Torre, Cristina; Casanova, Isolda; Acosta, Gerardo; Coll Merino, Mª Carmen; Moreno, María José; Albericio, Fernando; Aznar, Elena; Mangues, Ramón; Royo, Miriam; Sancenón Galarza, Félix; Martínez-Máñez, Ramón (Wiley, 2015-02-04)

[EN] B-cell non-Hodgkin s lymphoma (B-NHL) is the most frequent malignant lymphoid neoplasm, which has a high degree of relapse and chemoresist-ance. Thus, strategies to improve currently used therapies are needed. In this ...
Gated Silica Mesoporous Materials in Sensing Applications

Sancenón Galarza, Félix; Pascual, Lluís; Oroval, Mar; Aznar Gimeno, Elena; Martínez-Máñez, Ramón (Wiley Open Access, 2015-08)

[EN] Silica mesoporous supports (SMSs) have a large specific surface area and volume and are particularly exciting vehicles for delivery applications. Such container-like structures can be loaded with numerous different ...
Hexametaphosphate-Capped Silica Mesoporous Nanoparticles Containing CuII Complexes for the Selective and Sensitive Optical Detection of Hydrogen Sulfide in Water

El Sayed Shehata Nasr, Sameh; Milani, Michele; Licchelli, Maurizio; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (John Wiley & Sons, 2015)

[EN] CuII-macrocycle functionalized hexametaphosphate-capped silica mesoporous nanoparticles have been prepared and used for the selective and sensitive detection of hydrogen sulfide in aqueous environments. The possibility ...
Mesoporous silica microparticles gated with a bulky azo derivative for the controlled release of dyes/ drugs in colon

Ferri, Daniel; Gaviña, Pablo; Parra Álvarez, Margarita; Costero, Ana M.; El Haskouri, Jamal; Amorós del Toro, Pedro; Merino Sanjuán, Virginia; Teruel, Adrián H; Sancenón Galarza, Félix; Martínez-Máñez, Ramón (The Royal Society, 2018-08)

[EN] Mesoporous silica microparticles were prepared, loaded with the dye safranin O (M-Saf) or with the drug budesonide (M-Bud) and capped by the grafting of a bulky azo derivative. Cargo release from M-Saf at different ...
Nanostructured Supports for Detection of Pathogens and Biomolecules of Interest Based on Molecular Gates with Oligonucleotides

Aranda Sobrino, María de las Nieves (Universitat Politècnica de València, 2024-11-03)

[ES] La tesis doctoral "Nanostructured supports for the detection of pathogens and biomolecules of interest based on molecular gates with oligonucleotides" se centra en el diseño de nanomateriales híbridos orgánico-inorgánicos ...
New Advances in In Vivo Applications of Gated Mesoporous Silica as Drug Delivery Nanocarriers

García-Fernández, Alba; Aznar, Elena; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (John Wiley & Sons, 2020-01-23)

[EN] One appealing concept in the field of hybrid materials is related to the design of gated materials. These materials are prepared in such a way that the release of chemical or biochemical species from voids of porous ...
Overview of the Evolution of Silica-Based Chromo-Fluorogenic Nanosensors

Pla, Luis; Lozano-Torres, Beatriz; Martínez-Máñez, Ramón; Sancenón Galarza, Félix; Ros-Lis, José Vicente (MDPI AG, 2019-11-23)

[EN] This review includes examples of silica-based, chromo-fluorogenic nanosensors with the aim of illustrating the evolution of the discipline in recent decades through relevant research developed in our group. Examples ...
Pseudorotaxane capped mesoporous silica nanoparticles for 3,4-methylenedioxymethamphetamine (MDMA) detection in water

Lozano-Torres, Beatriz; Pascual, Lluís; Bernardos Bau, Andrea; Marcos Martínez, María Dolores; Jeppesen, Jan Oskar; Salinas Soler, Yolanda; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (The Royal Society of Chemistry, 2017-03-28)

[EN] Mesoporous silica nanoparticles loaded with fluorescein and capped by a pseudorotaxane, formed between a naphthalene derivative and cyclobis(paraquat-p-phenylene) (CBPQT(4+)), were used for the selective and sensitive ...
Selective, Highly Sensitive, and Rapid Detection of Genomic DNA by Using Gated Materials: Mycoplasma Detection

Climent Terol, Estela; Mondragón Martínez, Laura; Martínez Mañez, Ramón; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Murguía Ibáñez, José Ramón; Amoros del Toro, Pedro Jose; Rurack, Knut; Pérez Payá, Enrique (Wiley-VCH Verlag, 2013-07-10)

The coupling of gated-indicator delivery with highly specific biochemical recognition is an innovative strategy for the detection of DNA sequences, able to compete with classical methods which need PCR amplification, in ...
Simple Endotoxin Detection Using Polymyxin-B-Gated Nanoparticles

Otri, Ismael; El Sayed, Sameh; Medaglia, Serena; Martínez-Máñez, Ramón; Aznar, Elena; Sancenón Galarza, Félix (John Wiley & Sons, 2019-03-12)

[EN] A nanodevice based on mesoporous silica nanoparticles with rhodamine B in the pore framework, functionalized with carboxylates on the outer surface and capped with the cationic polymyxin B peptide, was used to selectively ...
Smart drug delivery systems designed to improve Inflammatory Bowel Disease therapy

Hernández Teruel, Adrián (Universitat Politècnica de València, 2019-10-21)

[ES] La presente tesis doctoral titulada "Sistemas de liberacio'n controlada de fa'rmacos diseñados para mejorar el tratamiento de Enfermedad Inflamatoria Intestinal" se centra en el diseño, preparación, caracterización y ...