Carretero Paulet, Lorenzo; Fares Riaño, Mario Ali(Oxford University Press (OUP), 2012-11)
[EN] Gene duplicates are a major source of evolutionary novelties in the form of new or specialized functions and play a key role in speciation. Gene duplicates are generated through whole genome duplications (WGD) or ...
Mattenberger, Florian; Sabater-Muñoz, Beatriz; Toft, Christina; Sablok, Gaurav; Fares Riaño, Mario Ali(Oxford University Press, 2017-12)
[EN] Gene duplication is an important source of novelties and genome complexity. What genes are preserved as duplicated through long evolutionary times can shape the evolution of innovations. Identifying factors that ...
The Bclass of MADS box genes has been studied in a wide range of plant species, but has remained largely uncharacterized in legumes. Here we investigate the evolutionary fate of the duplicated AP3-like genes of a legume ...
Fares Riaño, Mario Ali; Sabater-Muñoz, B.; Toft, C.(Oxford University Press, 2017-05-01)
[EN] Gene duplication generates new genetic material, which has been shown to lead to major innovations in unicellular and multicellular organisms. A whole-genome duplication occurred in the ancestor of Saccharomyces yeast ...
Carretero Paulet, Lorenzo; Albert, VA; Fares Riaño, Mario Ali(Oxford University Press (OUP), 2013-09)
[EN] The ubiquitous and conserved cytosolic heat-shock proteins 90 (HSP90A) perform essential functions in the cell. To understand the evolutionary origin of HSP90A functional diversification, we analyzed the distribution ...
Willemsen, Anouk; Zwart, Mark Peter; Higueras, Pablo; Sardanyes Cayuela, Jose; Elena Fito, Santiago Fco(Oxford University Press (OUP), 2016-09)
One of the striking features of many eukaryotes is the apparent amount of redundancy in coding and non-coding elements of their genomes. Despite the possible evolutionary advantages, there are fewer examples of redundant ...
Caffrey, Brian E.; Williams, Tom A.; Jiang, Xiaowei; Toft, Christina; Hokamp, Karsten; Fares Riaño, Mario Ali(Public Library of Science, 2012-04)
Functional divergence is the process by which new genes and functions originate through the modification of existing ones.
Both genetic and environmental factors influence the evolution of new functions, including gene ...
[EN] Biological systems are resistant to perturbations caused by the environment and by the intrinsic noise of the system. Robustness to mutations is a particular aspect of robustness in which the phenotype is resistant ...
Gallego-Bartolome, Javier; Minguet, E.G.; Marin, Jaime A.; Prat, Salomé; BLAZQUEZ RODRIGUEZ, MIGUEL ANGEL; ALABADÍ DIEGO, DAVID(Oxford University Press, 2010-06)
[EN]
Plasticity and robustness of signaling pathways partly rely on genetic redundancy, although the precise mechanism that provides functional specificity to the different redundant elements in a given process is often ...