García-Simón, Alberto; León-Palacio, Ana; REYES ROMÁN, JOSÉ FABIÁN; Casamayor Rodenas, Juan Carlos; Pastor López, Oscar(Institute of Electrical and Electronics Engineers, 2021)
[EN] Precision medicine has emerged as a disrupting medical model to transform a historically reactive medicine into a proactive one that focuses on delivering individualized treatment. A relevant challenge of precision ...
Blasco Mateu, Agustín; Toro, Miguel Angel(Elsevier, 2014-08)
[EN] Two scientific schools have been in coexistence from the beginning of genetics, one of them searching for factors of inheritance and the other one applying biometrical models to study the relationships between relatives. ...
[EN] Volatile profile of melon fruit from 25 introgression lines (ILs), developed by introgressing specific genomic regions from the Japanese cultivar `Ginsen makuwa¿ (MAK) into the `Charentais¿ recurrent genetic background ...
Pérez de Castro, Ana María; Vilanova Navarro, Santiago; Cañizares Sales, Joaquín; Pascual Bañuls, Laura; Blanca Postigo, José Miguel; Díez Niclós, Mª José Teresa de Jesús; Prohens Tomás, Jaime; Picó Sirvent, María Belén(Bentham Science Publishers, 2012-05)
[EN] Plant breeding has been very successful in developing improved varieties using conventional tools and methodologies. Nowadays, the availability of genomic tools and resources is leading to a new revolution of plant ...
García-Simón, Alberto; Bernasconi, Anna; Guizzardi, Giancarlo; Pastor López, Oscar; Storey, Veda C.; Panach, Ignacio(Elsevier, 2023-09)
[EN] Although the knowledge about human genomics is available to all scientists, information about this scientific breakthrough can often be difficult to fully comprehend and share. A Conceptual Schema of the Human Genome ...
León Palacio, Ana(Universitat Politècnica de València, 2023-11-10)
This document describes a theoretical proposal for creating an Automated Virtual
Data Integration system (AVDIS) based on current solutions. The proposed
AVDIS aims to solve or mitigate the main problems derived from ...
Prohens Tomás, Jaime; Fita, Ana; Rodríguez Burruezo, Adrián; Raigón Jiménez, Mª Dolores; Plazas Ávila, María de la O; Vilanova Navarro, Santiago(Universidad de Estudios Agrícolas y Medicina Veterinaria Cluj-Napoca, 2011)
[EN] During the last century, conventional plant breeding, mostly based in the evaluation
at the phenotypic level, has been very successful in increasing the crop yields and in consequence the
global production of food. ...
Bellver Catalá, Marta(Universitat Politècnica de València, 2018-02-26)
[ES] La Leucemia Linfocítica Crónica B (LLC-B) es un síndrome linfoproliferativo heterogéneo e
incurable cuyos mecanismos de progresión tumoral no son totalmente conocidos.
Recientemente se ha descrito la presencia de ...
García-Simón, Alberto; Costa-Sánchez, Mireia; García-Zarzoso, Alba; Pastor López, Oscar(Oxford University Press, 2024-05-15)
[EN] Mutational hotspots are DNA regions with an abnormally high frequency of genetic variants. Identifying whether a variant is located in a mutational hotspot is critical for determining the variant's role in disorder ...
Van Der Kroon ., Matthijs(Universitat Politècnica de València, 2012-09-05)
Todays genomic domain evolves around insecurity: too many imprecise concepts, too much information to be properly managed. Considering that conceptualization is the most exclusive human characteristic, it makes full sense ...
Gramazio, Pietro; Alonso-Martín, David; Arrones-Olmo, Andrea; Villanueva-Párraga, Gloria; Plazas Ávila, María de la O; Toppino, Laura; Barchi, Lorenzo; Portis, Ezio; Ferrante, Paola; Lanteri, Sergio; Rotino, Giuseppe Leonardo; Giuliano, Giovanni; Vilanova Navarro, Santiago; Prohens Tomás, Jaime(Oxford University Press, 2023-10)
[EN] Eggplant (Solanum melongena) is a major vegetable crop with great potential for genetic improvement owing
to its large and mostly untapped genetic diversity. It is closely related to over 500 species of Solanum ...
Arenas Ortiz, Yaiza(Universitat Politècnica de València, 2015-09-04)
[EN] Legionella pneumophila is an environmental pathogenic bacterium. In Valencia, the bacterium causes outbreaks, which makes necessary the development of methods of control and surveillance. In the town of Alcoy, the ...
Carreño Bolufer, Jesús(Universitat Politècnica de València, 2023-10-11)
[ES] La mácula es una pequeña zona ubicada en la retina responsable de tareas cotidianas como la lectura, la conducción y la identificación de personas. Las enfermedades de la mácula impactan en una pérdida de la agudeza ...
Parres Montoya, Daniel(Universitat Politècnica de València, 2022-09-06)
[ES] La detección de variantes de ADN es una tarea importante y difícil en la Genómica. Las tecnologías de secuenciación de una sola molécula han conseguido revolucionar la detección de variantes genéticas, el ensamblaje ...
Berbegal Martínez, Mónica; Garzón, C. D.; Ortega, A.; Armengol Fortí, Josep; Jiménez Díaz, R. M.; Jiménez Gasco, María del Mar(Wiley, 2011-10)
The aim of this study was to develop new polymorphic markers for analysis of genetic diversity in the fungal soilborne plant pathogen Verticillium dahliae. Twelve polymorphic markers (five microsatellites and seven polymorphic ...
Roldán Pérez, Sergio(Universitat Politècnica de València, 2019-07-23)
[ES] El trabajo de fin de grado consistirá en el desarrollo e implementacion una herramienta bioinformática big data para el análisis de datos genómicos que se integrará en los proyectos BioData, CellBase y OpenCGA de la ...
León-Palacio, Ana; Pastor López, Oscar(Elsevier, 2021-11-15)
[EN] The management of the exponential growth of data that Next Generation Sequencing techniques produce has become a challenge for researchers that are forced to delve into an ocean of complex data in order to extract new ...
Vicente-Dolera, Nelly; Troadec, Christelle; Moya, Manuel; Río-Celestino, Mercedes del; Pomares-Viciana, Teresa; Bendahmane, Abdelhafid; Picó Sirvent, María Belén; Román, Belén; Gómez, Pedro(Public Library of Science, 2014-11)
Although the availability of genetic and genomic resources for Cucurbita pepo has increased significantly, functional genomic resources are still limited for this crop. In this direction, we have developed a high throughput ...
Moreno Molina, Miguel Ángel(Universitat Politècnica de València, 2023-11-06)
[ES] La resistencia a los antibióticos en la tuberculosis es un grave problema de salud mundial y un obstáculo creciente para el control de la enfermedad. En esta tesis utilizamos la genómica como herramienta para estudiar ...
Gramazio, Pietro; Prohens Tomás, Jaime; Plazas Ávila, María de la O; Mangino, Giulio; Herraiz García, Francisco Javier; García-Fortea, Edgar; Vilanova Navarro, Santiago(AcademicPres (EAP) Publishing House, 2018)
[EN] Dramatic advances in genomics during the last decades have led to a revolution in the field of vegetable crops breeding. Some vegetables, like tomato, have served as model crops in the application of genomic tools to ...