van Asten, Jordy G. M.; Latorre, Marcos; Karakaya, Cansu; Baaijens, Frank P. T.; Sahlgren, Cecilia M.; Ristori, Tommaso; Humphrey, Jay; Loerakker, Sandra(Springer-Verlag, 2023-10)
[EN] Blood vessels grow and remodel in response to mechanical stimuli. Many computational models capture this process phenomenologically, by assuming stress homeostasis, but this approach cannot unravel the underlying ...
Irons, Linda; Latorre, Marcos; Humphrey, Jay D.(Springer-Verlag, 2021-07)
[EN] Tissue-level biomechanical properties and function derive from underlying cell signaling, which regulates mass deposition, organization, and removal. Here, we couple two existing modeling frameworks to capture associated ...
Pfaller, Martin R; Latorre, Marcos; Schwarz, Erica L; Gerosa, Fannie M.; Szafron, Jason; Humphrey, Jay D.; Marsden, Alison L.(Elsevier, 2024-11-01)
[EN] Equilibrated fluid-solid-growth (FSGe) is a fast, open source, three-dimensional (3D) computa- tional platform for simulating interactions between instantaneous hemodynamics and long-term vessel wall adaptation through ...
Ramachandra, Abhay B.; Latorre, Marcos; Szafron, Jason M.; Marsden, Alison L.; Humphrey, Jay D.(Elsevier, 2020-10)
[EN] Vascular grafts have long been used to replace damaged or diseased vessels with considerable success, but a new approach is emerging where native vessels are merely supported, not replaced. Although external supports ...