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Antineoplastic tropolone derivatives as useful biomarkers: fluorescence enhancement upon binding to biological targets

Tormos Faus, Rosa Esperanza; Bosca Mayans, Francisco (Royal Society of Chemistry, 2013)

It has been observed for the first time that the binding of tropolone derivatives to human serum albumin (HSA) produce a high fluorescence promotion. Important evidence of the immobilization of these drugs into the protein ...
Intraprotein formation of a long wavelength absorbing complex and inhibition of excited state deprotonation in a chiral hydroxybiphenyl

Bonancía Roca, Paula; Vayá Pérez, Ignacio; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (American Chemical Society, 2012-12-27)

The two enantiomers of 2-(2-hydroxybiphenyl-4-yl)propanoic acid ((S)- and (R)-BPOH) have been selected as probes for human serum albumin (HSA). Photophysical characterization in the absence of protein led to emission maxima, ...

Mostrando ítems 1-2 de 2