Martín Guindal, Andrea(Universitat Politècnica de València, 2018-02-12)
Self-cleaving ribozymes such as the hammerhead (HHR), the hepatitis-¿ (HDV) or the twister (Tw) motifs, are a group of small catalytic RNAs with a numerous and widespread occurrence in the genomes of organisms from all ...
Muñoz Triviño, Jorge Jaime(Universitat Politècnica de València, 2021-07-30)
[ES] En el contexto de una pandemia mundial, ocasionada por el virus SARS-CoV2, que ha provocado más de cuatro millones de fallecidos en apenas más de un año, el surgimiento de nuevas estrategias terapéuticas para luchar ...
Carbonell, Alberto; Flores Pedauye, Ricardo; Gago Zachert, Selma Persida(Oxford University Press (OUP): Policy C - Option B, 2011)
[EN] Trans-cleaving hammerheads with discontinuous or extended stem I and with tertiary stabilizing motifs (TSMs) have been tested previously against short RNA substrates in vitro at low Mg2+ concentration. However, the ...