Montesinos Magraner, Marc; Vila, Carlos; Cantón, Rubén; Blay, Gonzalo; Fernández, Isabel; Muñoz Roca, María del Carmen; Pedro, José R.(Wiley, 2015)
A quinine-derived thiourea organocatalyst promoted
the highly enantioselective addition of naphthols and
activated phenols to ketimines derived from isatins. The
reaction afforded chiral 3-amino-2-oxindoles with a ...
Amr, Fares Ibrahim; Vila, Carlos; Blay, Gonzalo; Muñoz Roca, María del Carmen; Pedro, José R.(Wiley, 2016-05-19)
A quinine-derived thiourea catalysed the
enantioselective addition of 4-substituted pyrazolones
to isatin-derived ketimines, providing a variety
of aminooxindole-pyrazolone adducts containing
congested vicinal ...
Montesinos Magraner, Marc; Vila, Carlos; Rendón Patiño, Alejandra; Blay, Gonzalo; Fernández, Isabel; Muñoz Roca, María del Carmen; Pedro, José R.(American Chemical Society, 2016)
The first general catalytic method for the, so far elusive, enantioselective Friedel−Crafts functionalization of
indoles in the carbocyclic ring is presented. This transformation contrasts with the usual tendency of these ...
Vila, C.; Rendón-Patiño, A.; Montesinos-Magraner, M.; Blay, G.; Muñoz Roca, María Del Carmen; Pedro, J.R.(John Wiley & Sons, 2018-03-01)
[EN] A highly enantioselective addition of hydroxyquinolines to isatin-derived ketimines has been realized using a quinine-derived thiourea organocatalyst. The reaction affords chiral 3-amino-2-oxindoles bearing a quinoline ...
Vila, Carlos; Amr, Fares Ibrahim; Blay, Gonzalo; Muñoz Roca, María del Carmen; Pedro, José R.(Wiley, 2016-05-20)
An efficient one-pot asymmetric synthesis of
pyrazoles bearing a chiral quaternary stereocenter has
been developed. Quinine-derived thiourea catalyzed the
enantioselective addition of pyrazolones to isatin-derived
ketimines, ...