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Listar por palabra clave "Late sodium current"

RiuNet: Repositorio Institucional de la Universidad Politécnica de Valencia

Listar por palabra clave "Late sodium current"

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    Effects of the inhibition of late sodium current by GS967 on stretch-induced changes in cardiac electrophysiology 
    Canto Serrano, Irene Del; Santamaría, L.; Genovés, P.; Such-Miquel, Luis; Arias-Mutis, Óscar Julián; Zarzoso Muñoz, Manuel; Soler, C.; Parra-Giraldo, G.; Tormos Ferrando, Álvaro; Alberola, Antonio; Such Belenguer, Luis; Chorro, F.J. (Springer-Verlag, 2018)
    [EN] PurposeMechanical stretch increases sodium and calcium entry into myocytes and activates the late sodium current. GS967, a triazolopyridine derivative, is a sodium channel blocker with preferential effects on the late ...
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    In silico assessment of drug safety in human heart applied to late sodium current blockers 
    Trénor Gomis, Beatriz Ana; Gomis-Tena Dolz, Julio; Cardona Urrego, Karen Eliana; Romero Pérez, Lucia; Rajamani, Sridharan; Belardinelli, Luiz; Giles, Wayne R.; Saiz Rodríguez, Francisco Javier (Landes Bioscience, 2013-07-01)
    Drug-induced action potential (AP) prolongation leading to Torsade de Pointes is a major concern for the development of anti-arrhythmic drugs. Nevertheless the development of improved anti-arrhythmic agents, some of which ...