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Listar por palabra clave "Lung cancer"

Mostrando ítems 1-14 de 14

2D and 3D texture analysis to differentiate brain metastases on MR images: proceed with caution

Beresova, Monika; Larroza, Andrés; Arana, Estanislao; Varga, Jozsef; Balkay, Laszlo; Moratal, David (Springer-Verlag, 2018-04)

[EN] To find structural differences between brain metastases of lung and breast cancer, computing their heterogeneity parameters by means of both 2D and 3D texture analysis (TA). Patients with 58 brain metastases from ...
A Sonic Hedgehog Pathway Score to Predict the Outcome of Resected Non-Small Cell Lung Cancer Patients

Herreros-Pomares, Alejandro; Doria, Paula; Gallach, Sandra; Meri-Abad, Marina; Guijarro, Ricardo; Calabuig-Fariñas, Silvia; Camps, Carlos; Jantus-Lewintre, Eloisa (Springer, 2022-09-21)

[EN] Background Mutations and deregulations in components of the Hedgehog (Hh) pathway have been associated with cancer onset and tumor growth in different malignancies, but their role in non-small cell lung cancer (NSCLC) ...
Análisis de herramientas para acelerar la transferencia de conocimiento cientifico

Manukyan Melkumyan, Erika (Universitat Politècnica de València, 2018-02-14)

Lately, there has been an exponential advance in the biomedical field. Nonetheless these discoveries do not really mean direct mean direct benefits for the patients, or take a long time to arrive to the population. The ...
Caracterización de la Interacción entre Célula Madre Tumoral y Microambiente Inmune en el Cáncer de Pulmón no Microcítico

Torres Martínez, Susana (Universitat Politècnica de València, 2017-08-31)

Non-small cell lung cancer (NSCLC) is one of the solid tumors with the highest mortality in the world. The acquisition of treatment¿s resistances, together with the lack of treatment¿s effectiveness on Cancer Stem Cells ...
Characterization of Tumor Cells and Immune Microenvironment Interactions in Non Small Cell Lung Cancer. Translational implications

Torres Martínez, Susana (Universitat Politècnica de València, 2024-04-22)

[ES] En esta tesis, buscamos profundizar en el estudio del microambiente inmunitario del tumor (TME), lo que resultaría en una mejor caracterización del contexto inmunológico de los pacientes y la búsqueda de nuevos ...
Fifth Educational Symposium of the Spanish Lung Cancer Group: report on the Molecular Biology Workshop

Bover, Isabel; Rolfo, Christian; Jantus Lewintre, Eloisa; Sirera Pérez, Rafael; Camps, Carlos; Chaib, Imane; Ramirez-Serrano, Jose L.; Benlloch, Susana; Molina-Vila, Miguel Angel; Simonetti, Sara; Costa, Carlota; Gimenez-Capitan, Ana; Mendez, Pedro; Taron, Miguel; Rosell, Rafael (Elsevier, 2011-12)

The majority of non-small-cell lung cancer (NSCLC) patients present with locally advanced (35%) or metastatic disease (40%); in this setting, it is of the utmost importance to balance efficacy with toxicity. However, with ...
Fitocannabinoides como posibles agentes moduladores de la transición epitelio-mesénquima en cáncer de pulmón

Urbina Jara, Laura Keren (Universitat Politècnica de València, 2020-06-22)

[ES] El cáncer de pulmón es una de las principales enfermedades causantes de muerte actualmente en el mundo, por lo cual su estudio es imperativo. Los datos de GOBLOCAN 2012 muestran un índice de mortalidad en España por ...
Galacto-conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity

González-Gualda, Estela; Pàez-Rives, Marta; Lozano-Torres, Beatriz; Macias, David; Wilson III, Joseph R.; González-López, Cristina; Ou, Hui-Ling; MIrón-Barroso, Sofía; Zhang, Zhenguang; Lérida-Viso, Araceli; Blandez, Juan F.; Bernardos Bau, Andrea; Sancenón Galarza, Félix; Rovira, Miguel; Fruk, Ljiljana; Martins, Carla P.; Serrano, Manuel; Doherty, Gary J.; Martínez-Máñez, Ramón; Muñoz-Espín, Daniel (Blackwell Publishing, 2020-04)

[EN] Pharmacologically active compounds with preferential cytotoxic activity for senescent cells, known as senolytics, can ameliorate or even revert pathological manifestations of senescence in numerous preclinical mouse ...
Impacto de la tecnología de secuenciación masiva en el cáncer de pulmón no microcítico

Tébar Martínez, Roberto (Universitat Politècnica de València, 2016-09-05)

[ES] Introducción En el cáncer de pulmón no microcítico (CPNM) es necesaria la identificación de biomarcadores que permitan la caracterización molecular del tumor y, con ello, adecuar el manejo de los pacientes1. En este ...
Investigation of Complement Activation Product C4d as a Diagnostic and Prognostic Biomarker for Lung Cancer

Jantus Lewintre, Eloisa (Oxford University Press (OUP), 2013)

[EN] Background There is a medical need for diagnostic biomarkers in lung cancer. We evaluated the diagnostic performance of complement activation fragments. Methods We assessed complement activation in four bronchial ...
Lung Cancer and SARS-CoV-2 infection: Identifying important knowledge gaps for investigation

Rolfo, Christian; Meshulami, Noy; Russo, Alessandro; Krammer, Florian; Garcia-Sastre, Adolfo; Mack, Philip C.; Gomez, Jorge E.; Bhardwaj, Nina; Benyounes, Amin; Sirera Pérez, Rafael; Moore, Amy; Rohs, Nicholas; Henschke, Claudia I.; Yankelevitz, David; King, Jennifer (Elsevier, 2022-02)

[EN] Patients with lung cancer are especially vulnerable to coronavirus disease 2019 (COVID-19) with a greater than sevenfold higher rate of becoming infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...
miRNA detection methods and clinical implications in lung cancer

Usó, Marta; Jantus Lewintre, Eloisa; Sirera Pérez, Rafael; Bremnes, Roy M.; Camps, Carlos (Future Medicine, 2014)

[EN] Lung cancer is the leading cause of cancer death worldwide. Therefore, advances in the diagnosis and treatment of the disease are urgently needed. miRNAs are a family of small, noncoding RNAs that regulate gene ...
The role of tumor stroma in cancer progression and prognosis: emphasis on carcinoma-associated fibroblasts and non-small cell lung cancer

Bremnes, Roy M.; Donnem, Tom; Al-Saad, Samer; Al-Shibli, Khalid; Andersen, Sigve; Sirera Pérez, Rafael; Camps, Carlos; Marinez, Inigo; Busund, Lill-Tove (Lippincott, Williams & Wilkins, 2011-01)

[EN] Maintenance of both normal epithelial tissues and their malignant counterparts is supported by the host tissue stroma. The tumor stroma mainly consists of the basement membrane, fibroblasts, extracellular matrix, ...
The role of tumor-infiltrating immune cells and chronic inflammation at the tumor site on cancer development, progression, and prognosis: emphasis on non-small cell lung cancer

Bremnes, Roy M.; Al-Shibli, Khalid; Donnem, Tom; Sirera Pérez, Rafael; Al-Saad, Samer; Andersen, Sigve; Stenvold, Helge; Camps, Carlos; Busund, Lill-Tove (Lippincott, Williams & Wilkins, 2011-04)

[EN] In addition to malignant neoplastic cells, cancer tissues also include immune cells, fibroblasts, and endothelial cells, including an abundant collection of growth factors, proangiogenic mediators, cytokines, chemokines, ...