van Asten, Jordy G. M.; Latorre, Marcos; Karakaya, Cansu; Baaijens, Frank P. T.; Sahlgren, Cecilia M.; Ristori, Tommaso; Humphrey, Jay; Loerakker, Sandra(Springer-Verlag, 2023-10)
[EN] Blood vessels grow and remodel in response to mechanical stimuli. Many computational models capture this process phenomenologically, by assuming stress homeostasis, but this approach cannot unravel the underlying ...
Latorre, Marcos; Humphrey, Jay D.(Elsevier, 2020-08-15)
[EN] Constrained mixture models of soft tissue growth and remodeling can simulate many evolving conditions in health as well as in disease and its treatment, but they can be computationally expensive. In this paper, we ...
Irons, Linda; Latorre, Marcos; Humphrey, Jay D.(Springer-Verlag, 2021-07)
[EN] Tissue-level biomechanical properties and function derive from underlying cell signaling, which regulates mass deposition, organization, and removal. Here, we couple two existing modeling frameworks to capture associated ...
[EN] Biological growth and remodeling processes are necessarily time-dependent due to the finite periods needed for the material to be synthesized, deposited, degraded, and/or reorganized and, hence, so have been predominantly ...