Buscar en RiuNet

Listar

Todo RiuNet

Mi cuenta

Acceder

Ayuda RiuNet

Admin. UPV

Listar por palabra clave "Mesenchymal stem cells"

Mostrando ítems 1-20 de 25

Página siguiente

Agentes terapéuticos para la curación de heridas: testado in vitro de vesículas extracelulares secretadas de células mesenquimales estromales y omega 3

Merchán Herrera, Rocío Alba (Universitat Politècnica de València, 2020-10-07)

[ES] La curación de heridas es un proceso complejo que requiere la sincronización espacial y temporal de varios tipos celulares. Debido a su complejidad, este proceso puede sufrir complicaciones que deriven en un estancamiento ...
Biodegradable polyester networks including hydrophilic groups favor BMSCs differentiation and can be eroded by macrophage action

Fernández, Juan Manuel; Gisela Oberti, Tamara; Vikingsson, Line; Gómez Ribelles, José Luís; Cortizo, Ana (Elsevier, 2016-08)

[EN] The aim of this study is to show that introducing a small fraction of hydrophilic groups into a hydrophobic polyester favor the macrophage activity by accelerating the degradation action in aqueous media. It is also ...
Biomimetic microspheres for 3D mesenchymal stem cell culture and characterization

Clara-Trujillo, Sandra; Marin-Paya, Juan Carlos; Cordón, Lourdes; Sempere, Amparo; Gallego-Ferrer, Gloria; Gómez Ribelles, José Luís (Elsevier, 2019-05-01)

[EN] Stem cells reside in niches, specialized microenvironments that sustain and regulate their fate. Extracellular matrix (ECM), paracrine factors or other cells are key niche regulating elements. As the conventional 2D ...
Biophysical phenotyping of mesenchymal stem cells along the osteogenic differentiation pathway

Gavazzo, Paola; Viti, Federica; Donnelly, Hannah; Gonzalez Oliva, Mariana Azevedo; Salmerón Sánchez, Manuel; Dalby, Matthew J.; Vassalli, Massimo (Springer-Verlag, 2021-12)

[EN] Mesenchymal stem cells represent an important resource, for bone regenerative medicine and therapeutic applications. This review focuses on new advancements and biophysical tools which exploit different physical and ...
Compositional changes to synthetic biodegradable scaffolds modulate the influence of hydrostatic pressure on chondrogenesis of mesenchymal stem cells

Ródenas Rochina, Joaquín; Kelly, Daniel John; Gómez Ribelles, José Luís; Lebourg, Myriam Madeleine (IOP Publishing, 2016)

[EN] Mechanical cues such as hydrostatic pressure (HP) are known to regulate mesenchymal stem cell (MSC) differentiation. The fate of such cells is also strongly influenced by their substrate. The objective of this study ...
Culture of human bone marrow-derived mesenchymal stem cells on of poly(L-lactic acid) scaffolds: potential application for the tissue engineering of cartilage

Izal, Iñigo; Aranda, Pablo; Sanz Ramos, Patricia; Ripalda, Purificacion; Mora, Gonzalo; Granero Molto, Froilan; Deplaine, Harmony; Gómez Ribelles, José Luís; Gallego-Ferrer, Gloria; Acosta, Victor; Ochoa, Ignacio; García Aznar, Manuel; Andreu, Enrique J.; Monleón Pradas, Manuel; Doblare Castellano, Manuel; Prosper, Felipe (Springer Verlag, 2013-08)

Due to the attractive properties of poly(l-lactic acid) (PLLA) for tissue engineering, the aim was to determine the growth and differentiation capacity of mesenchymal stromal cells (MSCs) in PLLA scaffolds and their potential ...
Desarrollo de microcápsulas como vehículos de liberación de componentes bioactivos

Renart Romagosa, Nuria (Universitat Politècnica de València, 2024-09-02)

[ES] Este trabajo final de grado se enmarca en el proyecto de investigación Microentorno adaptativo para un modelo de enfermedad in vitro de mieloma múltiple PID2022-138572OB-C41. El objetivo del proyecto es avanzar en el ...
Design and characterization of microspheres for a 3D mesenchymal stem cell culture

Lastra, María Laura; Gómez Ribelles, José Luís; Cortizo, Ana María (Elsevier, 2020-12)

[EN] Recent studies have shown the relevance of growing mesenchymal stem cells (MSCs) in three-dimensional environments with respect to the monolayer cell culture on an adherent substrate. In this sense, macroporous scaffolds ...
Differentiation of mesenchymal stem cells for cartilage tissue engineering: Individual and synergetic effects of three-dimensional environment and mechanical loading

Panadero Pérez, Juan Alberto; Lanceros-Méndez, S.; Gómez Ribelles, José Luís (Elsevier, 2016)

[EN] The importance of biomechanical cues in chondrogenesis is well known. This paper reviews the existing literature on the effect of mechanical stimulation on chondrogenic differentiation of mesenchymal stem cells in ...
Effective elastin-like recombinamers coating on poly(vinylidene) fluoride membranes for mesenchymal stem cell culture

Guillot-Ferriols, María Teresa; del Barrio, Ana; Costa, Carlos M.; Lanceros-Méndez, Senentxu; Rodríguez-Cabello, José Carlos; Gómez Ribelles, José Luís; Santos, Mercedes; Gallego-Ferrer, Gloria (Elsevier, 2021-03-05)

[EN] Bone's inherent piezoelectricity is a key factor in regulating bone growth and mesenchymal stem cells (MSCs) fate towards the osteogenic lineage. The piezoelectric polymer poly(vinylidene) fluoride (PVDF) was thus ...
Electrical stimulation: Effective cue to direct osteogenic differentiation of mesenchymal stem cells?

Guillot-Ferriols, María Teresa; Lanceros-Méndez, Senentxu; Gómez Ribelles, José Luís; Gallego-Ferrer, Gloria (Elsevier, 2022-07)

[EN] Mesenchymal stem cells (MSCs) play a major role in bone tissue engineering (BTE) thanks to their capacity for osteogenic differentiation and being easily available. In vivo, MSCs are exposed to an electroactive ...
Electroactive Environments for Mesenchymal Stem Cells Osteogenic Differentiation

Guillot Ferriols, María Teresa (Universitat Politècnica de València, 2022-12-30)

[ES] El aumento de la esperanza de vida conlleva la aparición de problemas muscoloesqueléticos afectando a la calidad de vida de los pacientes. Las nuevas terapias regenerativas óseas se centran en el uso de las células ...
Extracellular Vesicles from Mesenchymal Stem Cells as Novel Treatments for Musculoskeletal Diseases

ALCARAZ TORMO, Mª JOSE; Compañ, Álvaro; Guillem Salazar, Mª Isabel (MDPI, 2019)

[EN] Mesenchymal stem/stromal cells (MSCs) represent a promising therapy for musculoskeletal diseases. There is compelling evidence indicating that MSC effects are mainly mediated by paracrine mechanisms and in particular ...
Extracellular vesicles: A new therapeutic strategy for joint conditions

Tofiño-Vian, Miguel; Guillen Salazar, Mª Isabel; Alcaraz Tormo, Mª Jose (Elsevier, 2018)

[EN] Extracellular vesicles (EVs) are attracting increasing interest since they might represent a more convenient therapeutic tool with respect to their cells of origin. In the last years much time and effort have been ...
Fast degrading polymer networks based on carboxymethyl chitosan

Gámiz González, Mª Amparo; Guldrís-Prada, Paula; Antolinos Turpín, Carmen María; Ródenas Rochina, Joaquín; Vidaurre, Ana; Gómez Ribelles, José Luís (Elsevier, 2017)

[EN] In this work macroporous membrane for mesenchymal stem cells, MSCs, transplant has been developed. The membranes support cell seeding and proliferation and completely degrade in less than one week in "in vitro" culture. ...
Influence of oxygen levels on chondrogenesis of porcine mesenchymal stem cells cultured in polycaprolactone scaffolds

Ródenas Rochina, Joaquín; Kelly, Daniel John; Gómez Ribelles, José Luís; Lebourg, Myriam Madeleine (John Wiley & Sons, 2017)

[EN] Chondrogenesis of mesenchymal stem cells (MSCs) is known to be regulated by a number of environmental factors, including local oxygen levels. The hypothesis of this study is that the response of MSCs to hypoxia is ...
Macroporous thin membranes for cell transplant in regenerative medicine

Antolinos Turpín, Carmen María; Morales Román, Rosa María; Ródenas Rochina, Joaquín; Gómez Ribelles, José Luís; Gómez-Tejedor, José Antonio (Elsevier, 2015-10)

The aim of this paper is to present a method to produce macroporous thin membranes made of poly (ethyl acrylate-co-hydroxyethyl acrylate) copolymer network with varying cross-linking density for cell transplantation and ...
Magnetically Activated Piezoelectric 3D Platform Based on Poly(Vinylidene) Fluoride Microspheres for Osteogenic Differentiation of Mesenchymal Stem Cells

Guillot-Ferriols, María Teresa; García-Briega, María Inmaculada; Tolosa, Laia; Costa, Carlos M.; Lanceros-Méndez, Senentxu; Gómez Ribelles, José Luís; Gallego-Ferrer, Gloria (MDPI, 2022-10)

[EN] Mesenchymal stem cells (MSCs) osteogenic commitment before injection enhances bone regeneration therapy results. Piezoelectric stimulation may be an effective cue to promote MSCs pre-differentiation, and poly(vinylidene) ...
Magnetically Activated Piezoelectric 3D Platform Based on Poly(Vinylidene) Fluoride Microspheres for Osteogenic Differentiation of Mesenchymal Stem Cells

Guillot Ferriols, María Teresa; García Briega, María Inmaculada; Tolosa Pardo, Laia; Costa, Carlos Miguel; Lanceros-Mendez, Senentxu; Gómez Ribelles, José Luís; Gallego Ferrer, Gloria (Universitat Politècnica de ValènciaMDPI, 2022-10-19)

Mesenchymal stem cells (MSCs) osteogenic commitment before injection enhances bone regen-eration therapy results. Piezoelectric stimulation may be an effective cue to promote MSC pre-differentiation, and poly(vinylidene) ...
Osteogenic differentiation of mesenchymal stem cells using hybrid nanofibers with different configurations and dimensionality

Gugutkov, Dencho; Awaja, Firas; Belemezova, Kalina; Keremidarska, Milena; Krasteva, Natalia; Kyurkchiev, Stanimir; Gallego-Ferrer, Gloria; Seker, Sukran; Elcin, Ayse Eser; Elçin, Yasar Murat; Altankov, George (John Wiley & Sons, 2017)

[EN] Novel, hybrid fibrinogen/polylactic acid (FBG/PLA) nanofibers with different configuration (random vs aligned) and dimensionality (2¿D vs 3¿D environment) were used to control the overall behavior and the osteogenic ...