Sánchez, Gerardo; Besada Ferreiro, Cristina María; Badenes, María Luisa; Monforte Gilabert, Antonio José; Granell Richart, Antonio(Public Library of Science, 2012-06)
[EN] Volatile compounds represent an important part of the plant metabolome and are of particular agronomic and biological interest due to their contribution to fruit aroma and flavor and therefore to fruit quality. By ...
Brun, Eva M.; Puchades, Rosa; Maquieira Catala, Ángel(Elsevier, 2011-05)
[EN] Doping control in sport is mandatory to detect and to control the use of prohibited substances. Due to the growing number of targets, the analysis of doping compounds and their metabolites is carried out using established ...
Jiménez Benavente, Eva(Universitat Politècnica de València, 2022-09-06)
[ES] El uso masivo de fertilizantes nitrogenados para maximizar la producción agrícola ha provocado graves problemas de polución ambiental, que se están intentando evitar en las nuevas normativas limitando el aporte de ...
[EN] Knowing the mechanisms that operate under water stress in commercial crops, particularly those that
can affect productivity, such as phenolic or cell wall metabolism, is becoming increasingly important in a
scenario ...
Marín Gómez, Juan(Universitat Politècnica de València, 2023-09-15)
[ES] El estrés metabólico en rumiantes presenta unos valores medios de diagnóstico clínicos del 10% aproximadamente y subclínicos del casi el 50%. Por norma general los casos estrés metabólico no atendidos terminan por ...
[EN] We compared the effects of milk-feeding in 288 Holstein calves (72 per group) which were fed twice (2F) or thrice (3F) daily, with or without the addition of hydrogenated fat-embedded calcium gluconate (G) supplemented ...
Palumbo, Fabrizio; García Lainez, Guillermo; Limones Herrero, Daniel; Coloma, María Dolores; Escobar, Javier; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel; Andreu Ros, María Inmaculada(Elsevier, 2016)
Chlorpromazine (CPZ) is an anti-psychotic drug widely used to treat disorders such as schizophrenia or manic-depression. Unfortunately, CPZ exhibits undesirable side effects such as phototoxic and photoallergic reactions ...
Calero Pons, Elena(Universitat Politècnica de València, 2019-09-04)
[ES] En este trabajo se ha estudiado la fotorreactividad del fármaco sulindaco (SLD), que es un antiinflamatorio no esteroideo (AINE), en disolución y en presencia de proteínas. También se ha investigado la fotorreactividad ...
Palomino-Schätzlein, Martina; Escrig Aparici, Pablo Vicente; Boira Tortajada, Herminio; Primo Millo, Jaime; Pineda-Lucena, Antonio; Cabedo Escrig, Nuria(American Chemical Society, 2011-10-09)
13C nuclear magnetic resonance (NMR) spectroscopy was explored as a simple and efficient technique for the quantitative analysis of nonpolar metabolites in plants. The method was first optimized with a mixture of known ...
Tamarit Mayo, Lorena(Universitat Politècnica de València, 2024-05-13)
[ES] Los inhibidores de la tirosina quinasa (TKIs) son fármacos anticancerígenos que actúan atacando selectivamente a las células cancerosas, inhibiendo su crecimiento descontrolado y, por tanto, la consiguiente aparición ...
Ferrer Ivorra, María Esperanza(Universitat Politècnica de València, 2016-05-19)
[EN] We work with a database of 143 biochemical compounds in two groups of patients with liver cirrhosis: 1) 26 patients with mild cognitive impairment, detected by performing psychometric tests and 2) 26 patients without ...
Chevilly-Tena, Sergio; Dolz-Edo, Laura; Blanca Postigo, José Miguel; Yenush, Lynne; Mulet, José Miguel(MDPI AG, 2023-01)
[EN] Broccoli (Brassica oleracea L. var. Italica Plenck) is a cruciferous crop that is considered to be a good source of micronutrients. Better taste is a main objective for breeding, as consumers are demanding novel ...
Torres Mayo, Alba(Universitat Politècnica de València, 2022-07-08)
[ES] La fibrosis quística (FQ) es un trastorno genético multisistémico que cursa con alteraciones gastrointestinales que dan lugar a malnutrición y malabsorción de macro y micronutrientes, así como a disbiosis intestinal. ...
García-Laínez, G.; Vayá Pérez, Ignacio; Marín, Mª Pilar; Miranda Alonso, Miguel Ángel; Andreu Ros, María Inmaculada(Springer-Verlag, 2021-01)
[EN] The epidermal growth factor receptors EGFR and HER2 are the main targets for tyrosine kinase inhibitors (TKIs). The quinazoline derivative lapatinib (LAP) is used since 2007 as dual TKI in the treatment of metastatic ...
Tamarit-Mayo, Lorena; El Ouardi, Meryem; Lence, Emilio; Andreu, Inmaculada; González-Bello, Concepción; Miranda Alonso, Miguel Ángel; Vayá Pérez, Ignacio(Frontiers Media SA, 2024-05-16)
[EN] The photobiological damage that certain drugs or their metabolites can photosensitize in proteins is generally associated with the nature of the excited species that are generated upon interaction with UVA light. In ...
Lope, Virginia; García-Pérez, Javier; Pérez-Gómez, Beatriz; Pedraza-Flechas, Ana María; Alguacil, Juan; González-Galarzo, María Carmen; Alba, Miguel Angel; van der Haar, Rudolf; Cortés Barragán, Rosa Ana; Pedraz-Pingarrón, Carmen; Moreo, María Pilar; Santamariña, Carmen; Ederra, María; Vidal, Carmen; Salas-Trejo, Dolores; Llobet Azpitarte, Rafael(Lippincott Williams & Wilkins, 2018-02)
[EN] Objectives The association between occupational exposures and mammographic density (MD), a marker of breast cancer risk, has not been previously explored. Our objective was to investigate the influence of occupational ...
Dolz Cortés, Ana(Universitat Politècnica de València, 2012-11-29)
[ES] El trabajo tiene como finalidad la obtención de una familia de metabolitos secundarios de interés para la industria a partir del cultivo de raíces aéreas en una especie concreta de plantas. Para ello se analizaran ...
Andreu Ros, María Inmaculada; Lence, Emilio; González-Bello, Concepción; Mayorga, Cristobalina; Cuquerella Alabort, Maria Consuelo; Vayá Pérez, Ignacio; Miranda Alonso, Miguel Ángel(Frontiers Media SA, 2020-10-30)
[EN] Lapatinib (LAP) is an anticancer drug generally used to treat breast and lung cancer. It exhibits hypersensitivity reactions in addition to dermatological adverse effects and photosensitivity. Moreover, LAP binds to ...
Rosa-Martínez, Elena; Adalid-Martinez, Ana Maria; Alvarado, Luis E.; Burguet-Belda, Resurrección; García-Martínez, María Dolores; Pereira-Días, Leandro; Casanova-Calancha, Cristina; Soler-Calabuig, Elena; Figás-Moreno, María Del Rosario; Plazas Ávila, María de la O; Prohens Tomás, Jaime; Soler Aleixandre, Salvador(Frontiers Media SA, 2021-04-07)
[EN] The 'de penjar' tomato (Solanum lycopersicum L.) is a group of local varieties from the Spanish Mediterranean region carrying the alc mutation, which provides long shelf-life. Their evolution under low-input management ...