[EN] The current criteria for diagnosing Alzheimer's disease (AD) require the presence of relevant cognitive deficits, so the underlying neuropathological damage is important by the time the diagnosis is made. Therefore, ...
Xie, Long; Wisse, Laura E. M.; Pluta, John; de Flores, Robin; Piskin, Virgine; Manjón Herrera, José Vicente; Wang, Hongzhi; Das, Sandhitsu R.; Ding, Song-Lin; Wolk, David A.; Yushkevich, Paul A.(John Wiley & Sons, 2019-08-15)
[EN] Medial temporal lobe (MTL) substructures are the earliest regions affected by neurofibrillary tangle pathology-and thus are promising biomarkers for Alzheimer's disease (AD). However, automatic segmentation of the MTL ...
Cutanda Montaña, Vicente Paul; Moratal, David; Arana Fernandez de Moya, Estanislao(Institute of Electrical and Electronics Engineers, 2015)
[EN] Alzheimer disease (AD) is the most common type of dementia and mild cognitive impairment (MCI) is a syndrome with an increased risk of developing dementia. As neuroimaging is relevant in their diagnosis, the purpose ...
Sanmartín Martínez, Jorge(Universitat Politècnica de València, 2024-09-09)
[ES] La enfermedad de Alzheimer representa una carga creciente para la salud pública, con una prevalencia en constante aumento en las últimas décadas. Se caracteriza por un deterioro progresivo de funciones cognitivas, ...
Romero Gómez, José Enrique; Coupe, Pierrick; Manjón Herrera, José Vicente(Elsevier, 2017-12)
[EN] The importance of the hippocampus in the study of several neurodegenerative diseases such as Alzheimer's disease makes it a structure of great interest in neuroimaging. However, few segmentation methods have been ...
Hett, Kilian; Ta, Vinh-Thong; Oguz, Ipek; Manjón Herrera, José Vicente; Coupé, Pierrick; Alzheimers Disease Neuroimaging Initiative(Elsevier, 2021-01)
[EN] The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer¿s disease (AD) is clinically relevant, and may above all have a significant impact on accelerating the development of new ...
[EN] Alzheimer's disease is the most common type of dementia in the elderly. It is a progressive degenerative disorder that may begin to develop up to 15 years before clinical symptoms appear. The identification of early ...
[EN] Introduction: Brain tractography is a non-invasive medical imaging technique which enables in vivo visualisation and various types of quantitative studies of white matter fibre tracts connecting different parts of the ...