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Mostrando ítems 1-4 de 4

Analytical fusion of multimodal magnetic resonance imaging to identify pathological states in genetically selected Marchigian Sardinian alcohol-preferring (msP) rats

Cosa Liñán, Alejandro (Universitat Politècnica de València, 2017-11-06)

[EN] Alcohol abuse is one of the most alarming issues for the health authorities. It is estimated that at least 23 million of European citizens are affected by alcoholism causing a cost around 270 million euros. Excessive ...
Increased network centrality of the anterior insula in early abstinence from alcohol

Bordier, C; Weil, Georg; Bach, Patrick; Scuppa, G; Nicolini , C; Forcellini, G; Pérez-Ramírez, María Úrsula; Moratal, David; Canals-Gamoneda, Santiago; Hoffmann, Sabine; Hermann, Derik; Vollstädt-Klein, Sabine; Kiefer, Falk; Kirsch, Peter; Sommer, W (Blackwell Publishing, 2022-01)

[EN] Abnormal resting-state functional connectivity, as measured by functional magnetic resonance imaging (MRI), has been reported in alcohol use disorders (AUD), but findings are so far inconsistent. Here, we exploited ...
Incubation of neural alcohol cue reactivity after withdrawal and its blockade by naltrexone

Bach, Patrick; Weil, Georg; Pompili, Enrico; Hoffmann, Sabine; Hermann, Derik; Vollstädt-Klein, Sabine; Mann, Karl; Pérez-Ramírez, Úrsula; Moratal, David; Canals, Santiago; Dursun, Serdar M.; Greenshaw, Andrew J.; Kirsch, Peter; Kiefer, Falk; Sommer, Wolfgang H. (Blackwell Publishing, 2020-01)

[EN] During the first weeks of abstinence, alcohol craving in patients may increase or "incubate." We hypothesize that Naltrexone (NTX) blocks this incubation effect. Here, we compared NTX effects on neural alcohol cue ...
Multi-modal MRI classifiers identify excessive alcohol consumption and treatment effects in the brain

Cosa, Alejandro; Moreno, Andrea; Pacheco-Torres, Jesús; Ciccocioppo, Roberto; Hyytiä, Petri; Sommer, Wolfgang H.; Moratal, David; Canals, Santiago (Blackwell Publishing, 2017)

[EN] Robust neuroimaging markers of neuropsychiatric disorders have proven difficult to obtain. In alcohol use disorders, profound brain structural deficits can be found in severe alcoholic patients, but the heterogeneity ...

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