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Mostrando ítems 1-3 de 3

Chemotherapy-induced neutropenia does not correlate with DNA repair gene polymorphisms and treatment efficacy in advanced non-small-cell lung cancer patients

Sirera Pérez, Rafael (Elsevier, 2011-07)

[EN] Background: Platinum doublets are standard chemotherapy for advanced non-small-cell lung cancer (NSCLC). The aim of this study was to assess whether neutropenia is: (1) an indicator for treatment efficacy, or (2) ...
Personalized Medicine in Infant Population with Cancer: Pharmacogenetic Pilot Study of Polymorphisms Related to Toxicity and Response to Chemotherapy

Urtasun, Andrea; Olivera, Gladys G.; Sendra, Luis; Aliño, Salvador F.; Berlanga, Pablo; Gargallo, Pablo; Hervás-Marín, David; Balaguer, Julia; Juan-Ribelles, Antonio; Andrés, María del Mar; Cañete, Adela; Herrero, María José (MDPI AG, 2023-03)

[EN] Simple Summary Cancer is still the leading cause of disease-related death in pediatric populations and an important source of morbidity. These can be due to the neoplasm itself but also to the treatment administered; ...
Phase II clinical trial with gemcitabine and paclitaxel sequential monotherapy as first-line treatment for advanced non-small-cell lung cancer (SLCG 01-04)

Iranzo, Vega; Sirera Pérez, Rafael; Carrato, Alfredo; Cabrera, Andrea; Jantus, Eloísa; Guijarro, Ricardo; Sanmartín, Elena; Blasco, Ana; Gil, Mireia; Gómez Aldaraví, Lorenzo; González Larriba, José Luis; Massuti, Bertomeu; Velasco, Amalia; Provencio, Mariano; Rosell, Rafael; Camps, Carlos (Springer, 2011-06)

[EN] Background: In advanced-stage (IIIB or IV) non-small-cell lung cancer (NSCLC), combination chemotherapy has demonstrated response rates of 20% and a 1-year survival rate of 30%. We conducted a multicentre, open-label, ...

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