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Mostrando ítems 1-5 de 5

Covalently crosslinked organophosphorous derivatives-chitosan hydrogel as a drug delivery system for oral administration of camptothecin

Martínez-Martínez, M.; Rodríguez Berna, Guillermo; Bermejo, Marival; Gonzalez-Alvarez, Isabel; Gonzalez -Alvarez, Marta; Merino, Virginia (Elsevier, 2019-03)

[EN] Hydrogels are widely studied as drug delivery system. In this work we propose the employment of tetrakis (hydroxymethyl)phosphonium chloride as crosslinking agent to obtain covalent hydrogels based on chitosan. These ...
Curcumin or quercetin loaded nutriosomes as oral adjuvants for malaria infections

Fulgheri, Federica; Aroffu, Matteo; Ramírez, Miriam; Román-Álamo, Lucía; Peris, José Esteban; Usach, Iris; Nácher Alonso, Mª Amparo; Manconi, Maria; Fernàndez-Busquets, Xavier; Manca, Maria Letizia (Elsevier, 2023-08-25)

[EN] Artemisinin, curcumin or quercetin, alone or in combination, were loaded in nutriosomes, special phospholipid vesicles enriched with Nutriose FM06 (R), a soluble dextrin with prebiotic activity, that makes these ...
Immune responses induced in rabbits after oral administration of bovine serum albumin in combination with different adjuvants (herb extracts, aluminium hydroxide and platinum nanoparticles)

Bižanov, G.; Ramanavičienė, A.; Normantienė, T.; Jonauskienė, I. (Universitat Politècnica de València, 2016-12-28)

[EN] The aim of the current study was to evaluate the immunostimulatory activity of 10 different herbal extracts from Vitex agnus-castus, Vinca major, Aloe arborescens and the polyherbal product containing extracts from ...
pH-Dependent Molecular Gate Mesoporous Microparticles for Biological Control of Giardia intestinalis

Gonzalez-Alvarez, Isabel; Vivancos, Verónica; Coll Merino, Mª Carmen; Sánchez-Dengra, B.; Aznar, Elena; Ruiz Picazo, Alejandro; Bermejo, Marival; Sancenón Galarza, Félix; Dea-Ayuela, M. Auxiliadora; Gonzalez -Alvarez, Marta; Martínez-Máñez, Ramón (MDPI AG, 2021-01)

[EN] Giardiasis is a parasitism produced by the protozoa Giardia intestinalis that lives as trophozoite in the small intestine (mainly in the duodenum) attached to the intestinal villus by means of billed discs. The first ...
Semisynthesis, Cytotoxic Activity, and Oral Availability of New Lipophilic 9-Substituted Camptothecim Derivatives

Rodríguez Berna, Guillermo; Díaz Cabañas, Mª José; Mangas Sanjuan, Víctor; Gonzalez Alvarez, Marta; Gonzalez Álvarez, Isabel; Abasolo, Ibane; Simo Schwartz, Jr.; Bermejo, Marival; Corma Canós, Avelino (American Chemical Society, 2013-05-28)

Despite that 9-substituted camptothecins are promising candidates in cancer therapy, the limited accessibility to this position has reduced the studies of these derivatives to a few standard modifications. We report herein ...

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