[EN] Background: Epidermal growth factor receptor (EGFR) is overexpressed in a variety of epithelial malignancies including lung cancer. A soluble fragment of the EGFR extracellular domain (sEGFR) can be detected in the ...
[EN] Background: Platinum doublets are standard chemotherapy for advanced non-small-cell lung cancer (NSCLC). The aim of this study was to assess whether neutropenia is: (1) an indicator for treatment efficacy, or (2) ...
Álvarez-Torres, María del Mar; Fuster García, Elíes; Reynes, Gaspar; Juan-Albarracín, Javier; Chelebian-Kocharyan, Eduard Artur; Oleaga, Laura; Pineda, Jose; Auger, Cristina; Rovira, Alex; Emblem, Kyrre E.; Filice, Silvano; Molla-Olmos, Enrique; Garcia-Gomez, Juan M(John Wiley & Sons, 2021-04)
[EN] Introduction: IDH1/2 wt glioblastoma (GB) represents the most lethal tumour of the central nervous system. Tumour vascularity is associated with overall survival (OS), and the clinical relevance of vascular markers, ...
Urtasun, Andrea; Olivera, Gladys G.; Sendra, Luis; Aliño, Salvador F.; Berlanga, Pablo; Gargallo, Pablo; Hervás-Marín, David; Balaguer, Julia; Juan-Ribelles, Antonio; Andrés, María del Mar; Cañete, Adela; Herrero, María José(MDPI AG, 2023-03)
[EN] Simple Summary Cancer is still the leading cause of disease-related death in pediatric populations and an important source of morbidity. These can be due to the neoplasm itself but also to the treatment administered; ...
[EN] Background: In advanced-stage (IIIB or IV) non-small-cell lung cancer (NSCLC), combination chemotherapy has demonstrated response rates of 20% and a 1-year survival rate of 30%. We conducted a multicentre, open-label, ...
Álvarez-Torres, María del Mar; Juan-Albarracín, Javier; Fuster García, Elíes; Bellvís-Bataller, Fuensanta; Lorente, David; Reynés, Gaspar; Font de Mora, Jaime; Aparici-Robles, Fernando; Botella, Carlos; Muñoz-Langa, Jose; Faubel, Raquel; Asensio-Cuesta, Sabina; García-Ferrando, Germán A.; Chelebian, Eduard; Auger, Cristina; Pineda, Jose; Rovira, Alex; Oleaga, Laura; Mollà Olmos, Enrique; Revert, Antonio J.; Tshibanda, Luaba; Crisi, Girolamo; Emblem, Kyrre E.; Martin, Didier; Due-Tønnessen, Paulina; Meling, Torstein R.; Filice, Silvano; Sáez Silvestre, Carlos; Garcia-Gomez, Juan M(John Wiley & Sons, 2020-05)
[EN] Background Glioblastoma (GBM) is the most aggressive primary brain tumor, characterized by a heterogeneous and abnormal vascularity. Subtypes of vascular habitats within the tumor and edema can be distinguished: high ...
Qualitative analysis of circulating DNA in the blood is a promising non-invasive diagnostic and prognostic tool. Our aim was to study the association between the presence of KRAS mutations at codon 12 and several clinical ...
[EN] Aim: Telomeres are regions of highly repetitive, non-coding DNA located at the termini of chromosomes whose principal function is to maintain the structural stability of these ends. In 90% of human tumours, telomere ...