The preparation of novel fluorinated allylamines and their use as key fragments for the stereoselective synthesis of hydroxyethyl secondary amine (HEA)-type peptidomimetics is described. Our strategy employs chiral sulfinyl ...
Valle Ribera, Guillermo Samuel del(Universitat Politècnica de València, 2023-09-13)
[EN] Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic respiratory disorder marked by excessive lung tissue scarring. Integrin αVß6 is a crucial molecular player in the onset of pulmonary fibrosis. For different ...