[EN] One inhibitor of the fatty acid transporter FATP4 was synthesized in a three steps one-pot process in the presence of a bifunctional metal/acid catalyst. This molecule which has potential interest for the treatment ...
Gómez-Taylor Corominas, B.; Catalá Icardo, Mónica; Lahuerta Zamora, L.; García Mateo, J. V.; Martínez Calatayud, J.(Elsevier, 2004-10-20)
A direct chemiluminescent procedure for determination of hydroquinone based on the emergent flow methodology known as multicommutation or tandem-flow is presented for first time. The manifold was based on a set of three ...
This article deals with the simultaneous determination of three dissolution profiles with the aid of the new and emerging continuous-flow methodology known as multicommutation. This methodology is based on a flow network ...
There is a widespread perception that pharmaceutical R&D is facing a productivity crisis characterised by stagnation in the numbers of new drug approvals in the face of increasing R&D costs. This study explores pharmaceutical ...
[EN] Commercial drying methods are limited either by high production costs or significant quality loss due to process-related stresses. The near-ubiquitous use of freeze-drying in the pharmaceutical industry makes it the ...
Quílez López, Laura(Universitat Politècnica de València, 2019-10-14)
[ES] La eliminación de compuestos orgánicos persistentes (COPs) y en particular la de los fármacos, juega un importante papel en el tratamiento actual de las aguas residuales para llegar a lograr unas características en ...
Ciborowski, M.; Catalá Icardo, Mónica; García Mateo, J.V.; Martínez Calatayud, J.(Elsevier, 2004-11-19)
The present manuscript deals with a simple and sensitive flow-injection method for the chemiluminescent determination of thiazides. The method is based on the on-line photodegradation and chemiluminescent determination of ...
Yang, Huiru; García Gómez, Hermenegildo; Hu, Changwei(The Royal Society of Chemistry, 2024-03-04)
[EN] Amines are pivotal building blocks for a range of applications, including pharmaceuticals, polymers, agrochemicals, and organic synthesis. The hydrogenation of amides using molecular hydrogen via heterogeneous catalysis ...
Rodríguez Muñiz, Gemma María; Gomis Vicens, Juan; Arques Sanz, Antonio; Amat Payá, Ana María; Marín García, Mª Luisa; Miranda Alonso, Miguel Ángel(Wiley-Blackwell, 2014-11)
In this work, a kinetic model, in combination with time-resolved experiments, is applied to assess the involvement of OH in the photodegradation of emerging pollutants (EPs) by means of advanced oxidation processes. In ...
[EN] A flow injection analysis (FIA) manifold for the determination of penicillamine in pharmaceutical preparations is proposed. The manifold includes a solid-phase reactor for the in situ production of the derivatizing ...
Monfort Simó, Lidia(Universitat Politècnica de València, 2019-10-23)
[ES] El continuo aumento del consumo de fármacos tanto de uso humano como veterinario ha derivado en un problema medioambiental de grandes proporciones. Este grupo de productos, denominados Contaminantes Emergentes, entran ...
Arpagaus, Cordin(Editorial Universitat Politècnica de València, 2018-09-07)
[EN] Spray drying plays a crucial role in the processing of pharmaceutical products such as pills, capsules, and tablets as it is used to convert drug containing liquids into dried powdered forms. Nano spray drying is in ...
Kemp, Ian; van Millingen, Alex; Khaled, Houda; Iler, Lewis(Editorial Universitat Politècnica de València, 2018-09-07)
[EN] Simultaneous wetting and drying occur in processes such as fluid bed (top spray) granulation, Wurster coating and tablet film coating. This gives control challenges, as the spraying and evaporation processes must be ...
Martín Romacho, Juan Fernando(Universitat Politècnica de València, 2016-10-13)
[EN] Wastewater emerge as a major source of pharmaceuticals in the environment. Studies worldwide show that the treatments carried out by wastewater treatment plants (WWTP) are not suitable for the complete elimination of ...
Sciscenko, Iván Matías; García-Negueroles, Paula; Amat Payá, Ana María; Oller, Isabel; Escudero-Oñate, Carlos; Ferrando-Climent, Laura; Arqués Sanz, Antonio(MDPI AG, 2023-01)
[EN] In this work, we employed EEM-PARAFAC (fluorescence excitation-emission matrices-parallel factor analysis) as a low-cost tool to study the oxidation pathways of (fluoro)quinolones. Amounts of 12.5 ¿M of enrofloxacin ...