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Listar por palabra clave "Pharmacodynamic"

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New insights into the role of<i> VKORC1</i> polymorphisms for optimal warfarin dose selection in Caribbean Hispanic patients through an external validation of a population PK/PD model

Rodríguez-Fernández, Karine; Reynaldo-Fernández, G.; Reyes-González, Stephanie; de las Barreras, Camila; Rodríguez-Vera, Leyanis; Vlaar, Cornelis; Monbaliu, Jean-Christophe M.; Stelzer, Torsten; Duconge, Jorge; Mangas-Sanjuan, Victor (Elsevier, 2024-01)

[EN] Warfarin, an oral anticoagulant, has been used for decades to prevent thromboembolic events. The complex interplay between CYP2C9 and VKORC1 genotypes on warfarin PK and PD properties is not fully understood in special ...

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