[EN] Background and Objective: In silico methods are gaining attention for predicting drug-induced Torsade de Pointes (TdP) in different stages of drug development. However, many computational models tended not to account ...
Llopis-Lorente, Jordi; Baroudi, Samuel; Koloskoff, Kévin; Romero Pérez, Lucia; Mora-Fenoll, María Teresa; Basset, Matthieu; Benito, Sylvain; Dayan, Frederic; Saiz Rodríguez, Francisco Javier; Trénor Gomis, Beatriz Ana(Universitat Politècnica de València, 2023-03-29)
This repository contains the code used to generate the male and female population of models and simulate the different pharmacokinetic scenarios in Llopis-Lorente et al. (2023). Combining pharmacokinetic and electrophysiological ...