Buscar en RiuNet

Listar

Mostrando ítems 1-3 de 3

Considering Population Variability of Electrophysiological Models Improves the In Silico Assessment of Drug-Induced Torsadogenic Risk

Llopis Lorente, Jordi; Trénor Gomis, Beatriz Ana; Saiz Rodríguez, Francisco Javier (2022-05-13)

This repository contains the parameter sets of the population of TorORd models and the the population of ORdmD models, the ORdmD CellML file and MALTAB code used in Llopis-Lorente, J., Trenor, B., Saiz, J. (2022). Considering ...
Uncertainty Assessment of Proarrhythmia Predictions Derived from Multi-Level in Silico Models

Kopanska, Karolina; Rodríguez-Belenguer, Pablo; Llopis-Lorente, Jordi; Trénor, Beatriz; Saiz, Javier; Pastor, Manuel (Universitat Politècnica de València, 2023-02-14)

[EN] These datasets were generated to train ("PopulationDrugsTrainingKrNaLCaL.xlsx") and test ("PopulationDrugsTestKrCaLNaL.xlsx") the uncertainty assessment models developed in the paper "Uncertainty assessment of ...
When Does the IC50 Accurately Assess the Blocking Potency of a Drug?

Gomis-Tena Dolz, Julio; Brown, Brandon M.; Cano, Jordi; Trenor Gomis, Beatriz Ana; Yang, Pei-Chi; Saiz Rodríguez, Francisco Javier; Clancy, Colleen E.; Romero Pérez, Lucia (American Chemical Society, 2020-03-23)

[EN] Preclinical assessment of drug-induced proarrhythmicity is typically evaluated by the potency of the drug to block the potassium human ether-a-go-go-related gene (hERG) channels, which is currently quantified by the ...

Mostrando ítems 1-3 de 3