Saiz Rodríguez, Francisco Javier; Sanz i Carreras, Ferran; Pastor Maeso, Manuel; Trénor Gomis, Beatriz Ana; Gomis-Tena Dolz, Julio; Cano García, Jordi; Romero Pérez, Lucia(Universitat Politècnica de València, 2017-10-31)
This repository contains four Excel 2017 files named “APD.xlsx”, “QT.xlsx”, “Tx_APD.xlsx” and “Tx_QT.xlsx”. APD.xlsx and Tx_APD.xlsx files contain three sheets (called “Epi”, “Mid” and “Endo”), whereas the rest contain ...
Zemzemi, Nejib; Bernabeu, Miguel O.; Saiz Rodríguez, Francisco Javier; Cooper, Jonathan; Pathmanathan, Pras; Mirams, Gary R.; Pitt-Francis, Joe; Rodríguez, Blanca(Wiley-Blackwell, 2013-01)
BACKGROUND AND PURPOSE
Understanding drug effects on the heart is key to safety pharmacology assessment and anti-arrhythmic therapy development.
Here our goal is to demonstrate the ability of computational models to ...
Dux-Santoy Hurtado, Lydia; Sebastián Aguilar, Rafael; Felix-Rodriguez, Jose; Ferrero De Loma-Osorio, José María; Saiz Rodríguez, Francisco Javier(IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, 2011)
[EN] The use of antiarrhythmic drugs is common to treat heart rhythm disorders. Computational modeling and simulation are promising tools that could be used to investigate the effects of specific drugs on cardiac ...
Chowdhury, Md. Kamrul Hasan; Martínez-Mateu, Laura; Do, Jenny; Aromolaran, Kelly A.; Saiz Rodríguez, Francisco Javier; Aromolaran, Ademuyiwa(MDPI AG, 2021-10)
[EN] In the heart, the delayed rectifier K current, I-K, composed of the rapid (I-Kr) and slow (I-Ks) components contributes prominently to normal cardiac repolarization. In lipotoxicity, chronic elevation of pro-inflammatory ...