Pérez Cañamás, Miryam(Universitat Politècnica de València, 2015-07-27)
[EN] RNA silencing processes play an essential role in plant responses against exogenous nucleic acids such as transgenes, transposons or viruses. Viral-derived double-stranded RNAs (dsRNAs) trigger this type of processes ...
Díaz Jordá, Teresa(Universitat Politècnica de València, 2020-10-13)
[ES] Los virus de ARN son conocidos agentes causantes de algunas enfermedades graves en los seres humanos como la influenza, el VIH, la hepatitis C, Ébola, SARS, MERS o el reciente brote de la COVID19. La evolución de estos ...
Lalic ., Jasna; CUEVAS, J.M; Elena Fito, Santiago Fco(Public Library of Science, 2011-10-17)
Knowledge about the distribution of mutational fitness effects (DMFE) is essential for many evolutionary models. In recent years, the properties of the DMFE have been carefully described for some microorganisms. In most ...
[EN] DNA cytosine methylation is one of the main epigenetic mechanisms in higher eukaryotes
and is considered to play a key role in transcriptional gene silencing. In plants, cytosine methylation can
occur in all sequence ...
[EN] In plants, RNA silencing functions as a potent antiviral mechanism. Virus-derived double-stranded RNAs (dsRNAs) trigger this mechanism, being cleaved by Dicer-like (DCL) enzymes into virus small RNAs (vsRNAs). These ...
Tromas, Nicolas; Zwart, Mark Peter; Forment Millet, José Javier; Elena Fito, Santiago Fco(Oxford University Press, 2014)
[EN] Nonretroviral integrated RNA viruses (NIRVs) are genes of nonretroviral RNA viruses found in the genomes of many eukaryotic organisms. NIRVs are thought to sometimes confer virus resistance, meaning that they could ...
Zwart, Mark Peter; Elena Fito, Santiago Fco(American Phytopathological Society, 2015-01)
[EN] The independent action hypothesis is a simple model of pathogen infection that can make many useful predictions on infection kinetics and, therefore, a number of different tests of independent action have been developed. ...
Sardanyes Cayuela, Jose; Simó, Carles; Martínez, Regina; Solé, Ricard V.; Elena Fito, Santiago Fco(Nature Publishing Group, 2014-04-09)
[EN] The distribution of mutational fitness effects (DMFE) is crucial to the evolutionary fate of quasispecies. In this article we analyze the effect of the DMFE on the dynamics of a large quasispecies by means of a ...