Cano, Jordi; Zorio, Esther; Mazzanti, Andrea; Arnau, Miguel Ángel; Trenor Gomis, Beatriz Ana; Priori, Silvia G.; Saiz Rodríguez, Francisco Javier; Romero Pérez, Lucia(Frontiers Media SA, 2020-12-17)
[EN] The prolongation of the QT interval represents the main feature of the long QT syndrome (LQTS), a life-threatening genetic disease. The heterozygous SCN5A V411M mutation of the human sodium channel leads to a LQTS ...
Del-Canto, Irene; Gómez-Cid, Lidia; Hernández-Romero, Ismael; Guillem Sánchez, María Salud; Fernández-Santos, María Eugenia; Atienza, Felipe; Such, Luis; Fernández-Avilés, Francisco; Chorro, Francisco J.; Martínez Climent, Batiste Andreu(Frontiers Media SA, 2020-08-04)
[EN] Background Mechanical stretch increases Na(+)inflow into myocytes, related to mechanisms including stretch-activated channels or Na+/H(+)exchanger activation, involving Ca(2+)increase that leads to changes in ...